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Journal of Nursing ›› 2022, Vol. 29 ›› Issue (14): 37-42.doi: 10.16460/j.issn1008-9969.2022.14.037

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Best Evidence Summary of Intra-hospital Management of Intravenous Thrombolysis in Acute Ischemic Stroke

GAO Ping1,2a, ZHANG Biao-xin3, Song Gui-qi2b, Zhang Hai-ling2c, Shi Ke2c, Hu Wei2d   

  1. 1. School of Nursing, Anhui Medical University, Hefei 230022, China;
    2a. Dept. of Emergency; 2b. Education Section; 2c. Dept. of Nursing Administration; 2d. Dept. of Neurology, the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital), Hefei 230001,China;
    3. Dept. of Otolaryngology Head and Neck Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China
  • Received:2022-04-07 Online:2022-07-25 Published:2022-08-02

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Abstract: Objective To search, evaluate and integrate the best evidence of intra-hospital management of intravenous thrombolysis in acute ischemic stroke, and to provide basis for intra-hospital management of intravenous thrombolysis in patients with acute ischemic stroke. Methods Computer search was conducted for all the evidence published on UpToDate, BMJ Best Practice, GIN, SIGN, NICE, NGC, Cochrane Library, JBI, Embase, PubMed, OVID, Yimai Tong, CNKI, Wanfang Database from January 2011 to December 2021, including guidelines, systematic evaluation, evidence summary, recommended practice and expert consensus. Two researchers conducted quality evaluation, evidence extraction and evidence synthesis for eligible articles. Results Thirteen articles were collected, including 5 guidelines, 3 systematic evaluations, 1 evidence summary, and 4 expert consensus/position statements. Forty-three pieces of evidence were summarized from 7 dimensions including preview triage, evaluating severity, acute care, thrombolysis treatment, thrombolysis guardianship, complications nursing, quality management in acute ischemic stroke. Conclusion The evidence summary of intra-hospital management of intravenous thrombolysis in acute ischemic stroke can provide evidence-based practice basis for clinical practice. In evidence transformation, selective application of evidence should be combined with hospital environment, clinical practice and patient willingness, so as to improve patient outcomes.

Key words: ischemic stroke, intravenous thrombolysis, summary of evidence, evidence-based nursing

CLC Number: 

  • R459.7
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