Abstract: Objectives To describe the status of professional quality of life among oncology nurses, and to explore the influence factors. Methods By convenient sampling, a self-designed general questionnaire, the Chinese version of Professional Quality of Life Scale (ProQOL) and the Nurses' version of Health-promoting Lifestyle Profile (HPLP) were used to investigate 210 oncology nurses from 3 cancer-specialist hospitals in Guangzhou. Multiple linear regression analysis was conducted to analyze the influence factors. Results The raw scores of compassion satisfaction, burnout and secondary trauma stress were 31.69±5.71, 26.87±4.32 and 25.45±4.18 respectively. Oncology nurses with a moderate to high level of compassion satisfaction, burnout and secondary trauma stress accounted for 80.0%, 77.7% and 83.8% of the total, respectively. The total score of health-promoting lifestyle among oncology nurses was 60.00±14.21, indicating a moderate level of health-promoting lifestyle. Multiple linear regression analysis showed that self-realization, willingness to care for hospice patients, position/professional title entered into the multiple regression equation of compassion satisfaction（P<0.05）, explaining 42.0% of the total variance. Self-realization, development of interpersonal support, willingness to care for hospice patients, and whether the hospital had organized activities or lectures on psychological support for oncology nurses, entered into the multiple regression equation of burnout (P<0.05), explaining 37.8% of the total variance. Self-realization entered into the multiple regression equation of secondary traumatic（P<0.05）, explaining 1.6% of the total variance. Conclusion The level of compassion satisfaction and compassion fatigue among oncology nurses is relatively high. The professional quality of life among oncology nurses needs to be improved. Oncology nurses' self-realization, development of interpersonal support, willingness to care for the hospice patients, position/professional title and whether the hospital had organized activities or lectures on psychological support are the main influence factors. Nursing managers should pay attention to oncology nurses' professional quality of life, identify the factors that can be controlled in time, and take individualized intervention measures to keep their professional quality of life.

Key words: oncology, nurse, professional quality of life, health-promoting lifestyle