Abstract: Objective To explore the application effect of medical failure mode and effect analysis (FMEA) in pediatric intravenous drug admixture. Methods We established a FMEA team and drew a flow chart of pediatric intravenous drug admixture.Then we took measures for the improvement of projects with risk priority numbers≥8. The error rate of pediatric intravenous admixture and risk priority numbers of the failure modes before and after the implementation of FMEA was compared. Results The error rate of pediatric intravenous drug admixture was reduced from 0.120% to 0.026% and the difference was statistically significant (P<0.05). The risk priority numbers of the seven failure modes, such as mismatch between drug and the label, inaccurate doses, inconsistent amounts of solvents and labels, wrong sequence of parenteral nutrient solution admixture, leakage of syringes for micro-pump, foreign matter in the liquid and incomplete signature were significantly lower than before, showing statistical significance(P<0.05). Conclusion FEMA in pediatric intravenous drug admixture is effective for reducing the error rate, which is worthy to be promoted in clinical practice.

Key words: pediatric, pharmacy intravenous admixture service, healthcare failure mode and effect analysis, error rate