护理学报 ›› 2023, Vol. 30 ›› Issue (17): 34-38.doi: 10.16460/j.issn1008-9969.2023.17.034
经济毒性对慢性病患者不良健康结局影响的研究进展
王哲, 许惠靖, 王宇宇, 高歌, 王晓辉, 吴元虹, 吴善玉
- 延边大学 护理学院,吉林 延边朝鲜族自治州 133000
摘要： 目的 旨在综述慢性病患者经济毒性对不良健康结局影响的研究进展,以深入了解慢性病患者经济毒性与健康结果之间的关联。方法 通过检索知网、万方、Pubmed等国内外相关数据库,从经济毒性的概念、来源、对慢性病患者健康结局的影响进行综述。结果 经济毒性在慢性病相关领域被广泛关注,其来源分为直接成本和间接成本。慢性病患者经济毒性与不良健康结局之间存在密切关联,高经济毒性与患者心理不适、治疗依从性下降、生活质量降低和死亡风险增加密切相关。结论 经济毒性是一个重要的因素,影响着慢性病患者的健康结局。为了改善患者的健康结局,减轻经济毒性和提高生活质量,医护人员和社会工作者应重视经济毒性问题,通过完善医疗团队建设、加强医患沟通,促进共同决策、提供心理支持和干预等措施促进患者生活质量的提升。
中图分类号:
- R473.56
| [1] 董奥,张智月,王晓梅,等.癌症患者经济毒性的研究进展[J]. 上海护理, 2022,22(7):53-58.DOI:10.3969/j.issn.1009-8399.2022.07.013. [2] Zafar SY, Abernethy AP.Financial toxicity, Part I: a new name for a growing problem[J]. Oncology (Williston Park), 2013, 27(2): 80-81. DOI:10.1093/neuonc/nos295. [3] 况艺,孙艳玲,荆凤, 等. 癌症相关经济毒性概念分析[J]. 护理研究, 2021, 35(20): 3695-3700. DOI:10.12102/j.issn.1009-6493.2021.20.025. [4] Nogueira LA, Machado CaM, Marques A, et al. Implications of financial toxicity in the lives of cancer patients: a reflection[J]. Rev Gaucha Enferm, 2021, 42: e20200095. DOI:10.1590/1983-1447.2021.20200095. [5] De Souza JA, Yap BJ, Hlubocky FJ, et al.The development of a financial toxicity patient-reported outcome in cancer: The COST measure[J]. Cancer, 2014, 120(20):3245-3253. DOI:10.1002/cncr.28814. [6] 于慧会,毕雪,刘运泳. 中文版癌症患者报告结局的经济毒性量表信度和效度研究[J].中华流行病学杂志, 2017, 38(8):1118-1120. DOI:10.3760/cma.j.issn.0254-6450.2017.08.024. [7] Khera R, Valero-Elizondo J, Nasir K.Financial toxicity in atherosclerotic cardiovascular disease in the United States: current state and future directions[J]. J Am Heart Assoc, 2020, 9(19): e017793. DOI: 10.1161/JAHA.120.017793. [8] Valero-Elizondo J, Chouairi F, Khera R, et al.Atherosclerotic cardiovascular disease, cancer, and financial toxicity among adults in the United States[J]. JACC Cardio Oncol, 2021, 3(2): 236-246. DOI: 10.1016/j.jaccao.2021.02.006. [9] Bloomfeld RS, Bickston SJ.Financial toxicity in people with inflammatory bowel disease[J]. Inflammatory Bowel Diseases, 2020, 27(7): 1170-1171. DOI: 10.1093/ibd/izaa267. [10] Bergeron M, Ishman SL.Persistent obstructive sleep apnea burden on family finances and quality of life[J]. Otolaryngol Head Neck Surg, 2021, 165(3):483-489. DOI:10.1177/0194599820986566. [11] Carrera PM, Kantarjian HM, Blinder VS.The financial burden and distress of patients with cancer: understanding and stepping-up action on the financial toxicity of cancer treatment[J]. CA Cancer J Clin, 2018, 68(2):153-165. DOI:10.3322/caac.21443. [12] 戴国琳,巴桑吉巴,马爽. 我国抗癌药价格高昂的原因及相关措施研究[J].中国药事, 2020, 34(8): 956-961. DOI:10.16153/j.1002-7777.2020.08.015. [13] Anon.Monthly and median costs of cancer drugs at the time of FDA approval 1965-2016[J]. J Natl Cancer Inst, 2017, 109(8). DOI: 10.1093/jnci/djx173. [14] Zeng X, Peng L, Peng Y, et al.Economic evaluation of adding daratumumab to a regimen of bortezomib + dexamethasone in relapsed or refractory multiple myeloma: based on the latest updated analysis of CASTOR[J]. Clin Ther, 2020, 42(2):251-262. DOI:10.1016/j.clinthera.2019.12.007. [15] 何玉梅,李薇,朱贺, 等. 百令胶囊联合西医常规治疗方案治疗慢性肾衰竭的药物经济学研究[J].中国药事, 2022, 36(8): 862-871. DOI:10.16153/j.1002-7777.2022.08.003. [16] Jain T, Litzow MR.No free rides: management of toxicities of novel immunotherapies in ALL,including financial[J].Hematology Am Soc Hematol Educ Program, 2018,2018(1): 25-34. DOI:10.1182/asheducation-2018.1.25. [17] Abrams HR, Durbin S, Huang CX, et al.Financial toxicity in cancer care: origins, impact, and solutions[J]. Transl Behav Med, 2021, 11(11): 2043-2054. DOI: 10.1093/tbm/ibab091. [18] Nipp RD, Lee H, Gorton E, et al.Addressing the financial burden of cancer clinical trial participation: longitudinal effects of an equity intervention[J]. Oncologist,2019,24(8):1048-1055. DOI: 10.1634/theoncologist.2019-0146. [19] Huey RW, George GC, Phillips P, et al.Patient-reported out-of-pocket costs and financial toxicity during early-phase oncology clinical trials[J]. Oncologist, 2021, 26(7): 588-596. DOI: 10.1002/onco.13767. [20] Yabroff KR, Guy GP Jr, Ekwueme DU, et al.Annual patient time costs associated with medical care among cancer survivors in the United States[J]. Med Care, 2014, 52(7): 594-601. DOI: 10.1097/MLR.0000000000000151. [21] Tien T, Gkougkousis E, Allchorne P, et al.The use of healthcare services by prostate cancer patients in the last 12 months of life: how do we improve the quality of care during this period?[J]. J Palliat Care, 2021, 36(2): 93-97. DOI: 10.1177/0825859720975944. [22] Lee A, Shah K, Chino F.Assessment of parking fees at National Cancer Institute-designated cancer treatment centers[J]. JAMA Oncol, 2020, 6(8):1295-1297. DOI:10.1001/jamaoncol.2020.1475. [23] Sweet E.Debt-related financial hardship and health[J]. Health Educ Behav, 2021, 48(6): 885-891. DOI: 10.1177/1090198120976352. [24] Van Beek FE, Wijnhoven LMA, Holtmaat K, et al.Psychological problems among cancer patients in relation to healthcare and societal costs: a systematic review[J]. Psychooncology, 2021, 30(11):1801-1835. DOI:10.1002/pon.5753. [25] Casilla-Lennon MM, Choi SK, Deal AM, et al.Financial toxicity among patients with bladder cancer: reasons for delay in care and effect on quality of life[J]. J Urol, 2018, 199(5): 1166-1173. DOI: 10.1016/j.juro.2017.10.049. [26] Luyckx VA, Miljeteig I, Ejigu AM, et al.Ethical challenges in the provision of dialysis in resource-constrained environments[J]. Semin Nephrol, 2017, 37(3): 273-286. DOI: 10.1016/j.semnephrol.2017.02.007. [27] Nguyen NH, Khera R, Dulai PS, et al.ational estimates of financial hardship from medical bills and cost-related medication nonadherence in patients with inflammatory bowel diseases in the United States[J]. Inflamm Bowel Dis, 2021, 27(7): 1068-1078. DOI: 10.1093/ibd/izaa266. [28] Osborn CY, Kripalani S, Goggins KM, et al.Financial strain is associated with medication nonadherence and worse self-rated health among cardiovascular patients[J]. J Health Care Poor Underserved, 2017, 28(1): 499-513. DOI: 10.1353/hpu.2017.0036. [29] Inguva S, Priyadarshini M, Shah R, et al.Financial toxicity and its impact on health outcomes and caregiver burden among adult cancer survivors in the USA[J]. Future Oncol, 2022, 18(13): 1569-1581. DOI: 10.2217/fon-2021-1282. [30] Alshammari B, Noble H, Mcaneney H, et al.An exploration of symptom burden and its management, in Saudi Arabian patients receiving haemodialysis, and their caregivers: a mixed methods study protocol[J]. BMC Nephrol, 2019, 20(1): 250. DOI: 10.1186/s12882-019-1424-9. [31] Koskinen JP, Färkkilä N, Sintonen H, et al.The association of financial difficulties and out-of-pocket payments with health-related quality of life among breast, prostate and colorectal cancer patients[J]. Acta Oncol, 2019, 58(7): 1062-1068. DOI: 10.1080/0284186X.2019.1592218. [32] 袁静,林梦月,杨斌,等.前列腺癌患者经济毒性在自我效能与生活质量间的中介效应研究[J].解放军护理杂志, 2022,39(1):4-8.DOI:10.3969/j.issn.1008-9993.2022.01.002. [33] Parker C, Berkovic D, Ayton D, et al.Patient perceived financial burden in hematological malignancies: a systematic review[J]. Curr Oncol, 2022, 29(6): 3807-3824. DOI: 10.3390/curroncol29060305. [34] Ikonomou M, Skapinakis P, Balafa O, et al.The impact of socioeconomic factors on quality of life of patients with chronic kidney disease in Greece[J]. J Ren Care, 2015, 41(4): 239-246. DOI: 10.1111/jorc.12132. [35] Ng MSN, Chan DNS, Cheng Q, et al.Association between financial hardship and symptom burden in patients receiving maintenance dialysis: a systematic review[J].Int J Environ Res Public Health, 2021, 18(18). DOI:10.3390/ijerph18189541. [36] Hart NH, Smith AB, Hobbs K, et al.Juggling cancer and life in survivorship: the role of general practitioners[J]. Aust J Gen Pract, 2021, 50(8): 520-525. DOI: 10.31128/AJGP-04-21-5938. [37] Regueiro M, Click B, Anderson A, et al.Reduced unplanned care and disease activity and increased quality of life after patient enrollment in an inflammatory bowel disease medical home[J]. Clin Gastroenterol Hepatol, 2018, 16(11): 1777-1785. DOI: 10.1016/j.cgh.2018.04.007. |
| [1] | 李雯欣, 涂惠, 张娜, 陈祎慧, 谢丽丽, 于浪琴. 运动干预改善心血管病患者运动恐惧的研究进展[J]. 护理学报, 2024, 31(9): 24-27. |
| [2] | 李爱群, 李利花, 王芳, 蒋源元, 蔡益民. 慢性病资源利用在冠心病PCI术后患者自我超越与自我管理行为间的中介效应[J]. 护理学报, 2024, 31(6): 13-17. |
| [3] | 郑晓婷, 田霞, 王峥, 肖文莉. King达标理论在慢性病家庭护理中应用的范围综述[J]. 护理学报, 2024, 31(5): 56-60. |
| [4] | 姚心怡, 郑连雪. 刮痧在失眠治疗中的应用研究进展[J]. 护理学报, 2024, 31(23): 54-58. |
| [5] | 明清, 陶艳玲, 王明珠, 胡思鸿, 刘艳. 慢性病共病患者治疗负担相关体验的Meta整合[J]. 护理学报, 2024, 31(21): 55-61. |
| [6] | 武洁, 张培莉, 侯晓雅, 高超越, 刘雨溦, 张玉颖. 同伴支持在肿瘤患者营养管理中的研究进展[J]. 护理学报, 2024, 31(18): 30-34. |
| [7] | 胡玉兰, 陈英, 余艮珍, 王梦月. 儿科护士的慢性病患儿过渡期护理态度问卷编制及信效度检验[J]. 护理学报, 2024, 31(10): 64-69. |
| [8] | 陈彤, 秘玉清, 陈倩, 薛梓晨, 黄静雯, 罗盛, 李伟. 老年社区慢性病护理服务能力评价指标体系构建研究[J]. 护理学报, 2023, 30(7): 1-4. |
| [9] | 牛雨楠, 晋溶辰, 何娅娜, 黄金. 糖尿病足就诊延迟障碍因素及时间界定的研究进展[J]. 护理学报, 2023, 30(20): 16-18. |
| [10] | 钱怡, 周清平, 梁振宁, 王晨曦, 刘涵月, 于瑶, 玉素扑江·图尔荪, 王冬. 慢性病患者参与医患共同决策影响因素的Meta分析[J]. 护理学报, 2023, 30(20): 19-23. |
| [11] | 黎东梅, 陈锦丽, 李丽, 周娅楠. 300名慢性病患者代理决策者预立医疗照护计划参与现状及影响因素分析[J]. 护理学报, 2023, 30(2): 67-72. |
| [12] | 王贝贝, 段思雨, 冉明, 孙瑶, 李萍. 251例缺血性脑卒中患者复发风险感知现状及影响因素分析[J]. 护理学报, 2023, 30(15): 69-73. |
| [13] | 邓蓓, 艾亚婷, 胡慧, 周常青, 杨怡, 彭云巧. 轻度认知障碍患者预立医疗照护计划研究进展及启示[J]. 护理学报, 2022, 29(5): 37-41. |
| [14] | 张智月, 董奥, 冉明, 张国琴. 孤独在老年慢性病患者社会支持与自我感知老化间的中介效应[J]. 护理学报, 2022, 29(4): 59-63. |
| [15] | 杨丽潇, 周春兰, 屠燕, 谢翠华, 吴艳妮, 叶孝灵, 王润. 老年慢性病患者健康赋能需求评估量表的研制及信效度检验[J]. 护理学报, 2022, 29(3): 67-71. |
|
||