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护理学报 ›› 2020, Vol. 27 ›› Issue (6): 1-4.doi: 10.16460/j.issn1008-9969.2020.06.001

• 研究生园地 •    下一篇

恶性肿瘤患者握力的影响因素分析

卢婷, 应燕萍, 赵慧涵, 李倩, 徐谊, 凌瑛   

  1. 广西医科大学第一附属医院,广西 南宁 530021
  • 收稿日期:2019-12-13 出版日期:2020-03-25 发布日期:2020-07-13
  • 通讯作者: 应燕萍(1964-),女,广西南宁人,硕士,主任护师,副院长,硕士研究生导师。E-mail:yanpingying0116@126.com
  • 作者简介:卢婷(1995-),女,广西河池人,本科学历,硕士研究生在读。
  • 基金资助:
    国家自然科学基金项目(81860032); 广西自然科学基金项目(2018GXNSFAA050081); 广西壮族自治区卫生健康委员会青年基金(Z20190398)

Influence Factors of Handgrip Strength in Patients with Malignant Tumors

LU Ting, YING Yan-ping, ZHAO Hui-han, LI Qian, XU Yi, LING Yin   

  1. The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China
  • Received:2019-12-13 Online:2020-03-25 Published:2020-07-13

摘要: 目的 探讨恶性肿瘤患者握力的影响因素,以期为握力在恶性肿瘤患者营养评估中的应用奠定基础。方法 采用横断面调查研究方法,收集广西省某三级甲等医院肿瘤内科156例恶性肿瘤患者的临床资料,并测量其握力水平、人体测量学指标及实验室指标,使用营养风险筛查-2002(Nutritional Risk Screening-2002,NRS2002)进行营养风险评分,Pearson相关分析握力与营养相关人体测量学指标、实验室指标及NRS2002营养评分的相关性,采用多元线性回归分析恶性肿瘤患者握力的影响因素。结果 Pearson相关分析结果显示,恶性肿瘤患者握力水平与身高、体质量、体质指数、臂围、小腿围、血清白蛋白、血红蛋白、血肌酐呈正相关(P<0.05),与NRS2002营养评分呈负相关(P<0.05);多元线性回归分析结果显示,性别、年龄、血清白蛋白及NRS2002营养评分进入回归方程,共解释总变异的66.7%(P<0.05)。结论 性别、年龄、血清白蛋白及NRS2002营养评分情况是恶性肿瘤患者握力的影响因素。

关键词: 握力, 恶性肿瘤, 营养评估

Abstract: Objective To explore the factors affecting the handgrip strength of patients with malignant tumors. Methods A cross-sectional survey was used to collect clinical data of 156 patients with malignant tumors in the Oncology Department of a tertiary grade A hospital in Guangxi Province, and measure their handgrip strength, anthropometric indexes, and laboratory indexes. Nutritional Risk Screening-2002 (NRS2002) was used to analyze nutritional risk. Pearson correlation analysis was used to correlate handgrip strength with nutrition-related anthropometric indicators, laboratory tests, and NRS2002 nutrition score and multivariate linear regression to analyze the factors affecting the handgrip strength of patients with malignant tumors. Results The results of Pearson correlation analysis showed that the handgrip strength of patients with malignant tumors was positively correlated with height, weight, body mass index, arm circumference, calf circumference, serum albumin, hemoglobin, and blood creatinine (P<0.05), but negatively with the NRS2002 nutrition score (P<0.05). The results of multiple linear regression analysis showed that gender, age, serum albumin, and NRS2002 nutrition scores entered the regression equation, explaining 66.7% of the total variation (P<0.05). Conclusion Gender, age, serum albumin, and NRS2002 nutrition scores are factors affecting handgrip strength in patients with malignant tumors.

Key words: handgrip strength, malignant tumor, nutrition evaluation

中图分类号: 

  • R473.73
[1] Chen SC, Chung WS, Wu PY, et al.Associations among Geriatric Nutrition Risk Index, Bone Mineral Density, Body Composition and Handgrip Strength in Patients Receiving Hemodialysis[J]. Nutrition, 2019(65):6-12. DOI:10.1016/j.nut.2019.02.013.
[2] 代凤,苏迅,王蕾,等. 握力大小对留置PICC肿瘤患者腋静脉血流动力学的影响[J].护理学报,2019,26(1):8-11. DOI:10.16460/j.issn1008-9969.2019.01.008
[3] Valente KP, Almeida BL, Lazzarini TR, et al.Association of Adductor Pollicis Muscle Thickness and Handgrip Strength with Nutritional Status in Cancer Patients[J]. PLoS One, 2019,14(8):e0220334. DOI:10.1371/journal.pone.0220334.
[4] Norman K, Stobäus N, Gonzalez MC, et al.Hand Grip Strength: Outcome Predictor and Marker of Nutritional Status[J]. Clin Nutr, 2011,30(2):135-142. DOI:10.1016/j.clnu.2010.09.010.
[5] Alkan SB, Artaç M, Rak1c1oğlu N. The Relationship Between Nutritional Status and Handgrip Strength in Adult Cancer Patients: A Cross-Sectional Study[J]. Support Care Cancer, 2018,26(7):2441-2451. DOI:10.1007/s00520-018-4082-8.
[6] Ozorio GA, Barão K, Forones NM. Cachexia Stage, Patient-generated Subjective Global Assessment, Phase Angle, and Handgrip Strength in Patients with Gastrointestinal Cancer[J]. Nutr Cancer, 2017,69(5):772-779. DOI:10.1080/01635581.2017.1321130.
[7] Vodičar J, Pajek J, Hadžić V, et al.Relation of Lean Body Mass and Muscle Performance to Serum Creatinine Concentration in Hemodialysis Patients[J]. Biomed Res Int, 2018, 2018:4816536. DOI:10.1155/2018/4816536.
[8] 殷莹,郑璇,刘双玉,等. 不同握力方式对前臂预行动静脉内瘘血管条件的影响[J].护理研究,2018,32(1):99-102.
[9] 胡美玲. 维持性血液透析患者握力水平与营养状况的相关性分析[D].百色:右江民族医学院,2019.
[10] 董文,蔡开灿,蔡瑞君,等.营养风险筛查量表及其在食管癌患者中的应用进展[J].护理学报,2017,24(14):31-35.DOI:10.16460/j.issn1008-9969.2017.14.031.
[11] Kondrup J, Rasmussen HH, Hamberg O, et al.Nutritional Risk Screening (NRS 2002): A New Method Based on An Analysis of Controlled Clinical Trials[J]. Clin Nutr, 2003,22(3):321-336.DOI:10.1016/s0261-5614(02)00214-5.
[12] 郑雯雯,谢红浪,吕桂兰,等. 握力在老年糖尿病肾病病人营养评估中的应用价值[J].护理研究,2019,33(20):3474-3477.
[13] 林英,张静,时珍,等. 福州市养老机构老年人握力水平及影响因素[J].中国老年学杂志,2019,39(5):1226-1230.
[14] Auyeung TW, Lee SW, Leung J, et al.Age-associated Decline of Muscle Mass, Grip Strength and Gait Speed: A 4-year Longitudinal Study of 3018 Community-dwelling Older Chinese[J]. Geriatr Gerontol Int, 2014,14(Suppl 1):76-84. DOI:10.1111/ggi.12213.
[15] Lauretani F, Russo CR, Bandinelli S, et al.Age-associated Changes In Skeletal Muscles and their Effect on Mobility: An Operational Diagnosis of Sarcopenia[J]. J Appl Physiol (1985), 2003,95(5):1851-1860. DOI:10.1152/japplphysiol.00246.2003.
[16] Li B, Liu HY, Guo SH, et al.Impact of Early Enteral and Parenteral Nutrition on Prealbumin and High-sensitivity C-reactive Protein after Gastric Surgery[J].Genet Mol Res, 2015,14(2):7130-7135. DOI:10.4238/2015.June.29.6.
[17] 王洁,莫永珍,李咏阳,等. 社区老年人群握力与2型糖尿病的相关性分析[J].护理学报,2018,25(17):69-71. DOI:10.16460/j.issn1008-9969.2018.17.069.
[18] Zhang L, Lu Y, Fang Y.Nutritional Status and Related Factors of Patients with Advanced Gastrointestinal Cancer[J]. Br J Nutr,2014,111(7):1239-1244.DOI:10.1017/S000711451300367X.
[19] White JV, Guenter P, Jensen G, et al.Consensus Statement of the Academy of Nutrition and Dietetics/American Society for Parenteral and Enteral Nutrition:Characteristics Recommended for the Identification and Documentation of Adult Malnutrition (Undernutrition)[J]. J Acad Nutr Diet, 2012,112(5):730-738. DOI:10.1016/j.jand.2012.03.012.
[20] Barata AT, Santos C, Cravo M, et al.Handgrip Dynamometry and Patient-generated Subjective Global Assessment in Patients with Nonresectable Lung Cancer[J]. Nutr Cancer, 2017,69(1):154-158.DOI:10.1080/01635581.2017.1250923.
[21] Lidoriki I, Schizas D, Mpaili E, et al.Associations Between Skeletal Muscle Mass Index, Nutritional and Functional Status of Patients with Oesophago-gastric Cancer[J]. Clin Nutr ESPEN, 2019,34:61-67. DOI:10.1016/j.clnesp.2019.08.012.
[22] Riviati N, Setiati S, Laksmi PW, et al.Factors Related with Handgrip Strength in Elderly Patients[J]. Acta Med Indones, 2017,49(3):215-219.
[23] Knudsen AW, Naver A, Bisgaard K, et al.Nutrition Impact Symptoms, Handgrip Strength and Nutritional Risk in Hospitalized Patients with Gastroenterological and Liver Diseases[J]. Scand J Gastroenterol, 2015,50(10):1191-1198. DOI:10.3109/00365521.2015.1028994.
[24] Zhang XS, Liu YH, Zhang Y, et al.Handgrip Strength as a Predictor of Nutritional Status in Chinese Elderly Inpatients at Hospital Admission[J]. Biomed Environ Sci, 2017,30(11):802-810. DOI:10.3967/bes2017.108.
[25] Zhou J, Hiki N, Mine S, et al.Role of Prealbumin as a Powerful and Simple Index for Predicting Postoperative Complications after Gastric Cancer Surgery[J]. Ann Surg Oncol,2017,24(2):510-517.DOI:10.1245/s10434-016-5548-x.
[26] Olguín T, Bunout D, de la Maza MP, et al. Admission Handgrip Strength Predicts Functional Decline in Hospitalized Patients[J]. Clin Nutr Espen, 2017,17:28-32. DOI:10.1016/j.clnesp.2016.12.001.
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