妇科恶性肿瘤患者性健康研究进展

杜易梅, 刘莉, 郭立丽, 卢吉, 付苗苗, 刘杰

护理学报 ›› 2025, Vol. 32 ›› Issue (4) : 28-33.

PDF(986 KB)
PDF(986 KB)
护理学报 ›› 2025, Vol. 32 ›› Issue (4) : 28-33. DOI: 10.16460/j.issn1008-9969.2025.04.028
文献研究

妇科恶性肿瘤患者性健康研究进展

  • 杜易梅1a,2, 刘莉1a, 郭立丽1b, 卢吉1b, 付苗苗2, 刘杰2
作者信息 +
文章历史 +

摘要

目的 阐述妇科恶性肿瘤患者性健康的相关研究进展,为开展妇科恶性肿瘤患者性健康护理提供参考。方法 总结国内外文献研究,对妇科恶性肿瘤患者性健康的评估、研究现状、影响因素及干预措施进行综述。结果 妇科恶性肿瘤患者的性生理健康、性心理健康、伴侣关系健康及性社会文化健康均有不同程度的受损;可用于评估妇科恶性肿瘤患者性健康的评估工具有性健康问卷、性功能指数量表、宫颈癌和子宫内膜癌性幸福感量表等,评估工具多为国外开发,我国相关研究少见;妇科恶性肿瘤患者性健康受疾病及治疗、生理、社会心理等多种因素影响;干预措施有心理干预、物理疗法与运动干预、药物干预等。结论 妇科恶性肿瘤患者的性健康问题不容忽视,未来可基于现有研究开发适合我国国情文化的妇科恶性肿瘤患者的性健康评估工具,探索妇科恶性肿瘤患者性健康教育方案及干预方案,并开展相关的干预研究。

关键词

妇科恶性肿瘤 / 性健康 / 评估工具 / 影响因素 / 干预措施 / 综述

引用本文

导出引用
杜易梅, 刘莉, 郭立丽, 卢吉, 付苗苗, 刘杰. 妇科恶性肿瘤患者性健康研究进展[J]. 护理学报. 2025, 32(4): 28-33 https://doi.org/10.16460/j.issn1008-9969.2025.04.028
中图分类号: R473.73   

参考文献

[1] Bray F, Laversanne M, Sung H, et al.Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2024, 74(3): 229-263. DOI: 10.3322/caac.21834.
[2] Woopen H, Sehouli J, Davis A, et al.GCIG-Consensus guideline for Long-term survivorship in gynecologic Cancer: A position paper from the gynecologic cancer Intergroup (GCIG) symptom benefit committee[J]. Cancer Treatment Reviews, 2022,107:102396.DOI:10.1016/j.ctrv.2022.102396.
[3] Tounkel I, Nalubola S, Schulz A, et al.Sexual health screening for gynecologic and breast cancer survivors: a review and critical analysis of validated screening tools[J]. Sex Med, 2022, 10(2): 100498. DOI: 10.1016/j.esxm.2022.100498.
[4] Girard A, Arenella K, Rider GN, et al.Gynecologic cancer survivor preferences for provider communication regarding sexual health after treatment: a qualitative study[J]. Support Care Cancer, 2024, 32(10):629. DOI: 10.1007/s00520-024-08787-7.
[5] 杜易梅, 卢吉, 邢年路, 等. 宫颈癌患者性健康管理的最佳证据总结[J]. 中华现代护理杂志, 2024, 30(20): 2709-2715. DOI: 10.3760/cma.j.cn115682-20231221-02715.
[6] Sexual health - World Health Organization (WHO)[EB/OL]. (2024-01-15)[2024-01-21]. https://www.who.int/health-topics/sexual-health#tab=tab_2.
[7] Bober SL, Varela VS.Sexuality in adult cancer survivors: challenges and intervention[J]. J Clin Oncol, 2012, 30(30): 3712-3719. DOI: 10.1200/JCO.2012.41.7915.
[8] Cherven BO, Demedis J, Frederick NN.Sexual health in adolescents and young adults with cancer[J]. J Clin Oncol, 2023: Jco2301390. DOI: 10.1200/JCO.23.01390.
[9] Mitchell K R, Lewis R, O’sullivan LF, et al.What is sexual wellbeing and why does it matter for public health?[J]. Lancet Public Health, 2021, 6(8):e608-e613. DOI: 10.1016/S2468-2667(21)00099-2.
[10] 孙艳霞, 李莹, 刘明月, 等. 宫颈癌患者性健康护理培训方案的构建[J]. 中华护理杂志, 2022, 57(9): 1054-1060. DOI: 10.3761/j.issn.0254-1769.2022.09.005.
[11] Greimel E, Nagele E, Lanceley A, et al.Psychometric validation of the European Organisation for Research and Treatment of Cancer-Quality of Life Questionnaire Sexual Health (EORTC QLQ-SH22)[J]. Eur J Cancer, 2021, 154: 235-245. DOI: 10.1016/j.ejca.2021.06.003.
[12] Rosen R, Brown C, Heiman J, et al.The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function[J]. J Sex Marital Ther, 2000, 26(2):191-208. DOI:10.1080/009262300278597.
[13] Sun X, Li C, Jin L, et al.Development and validation of Chinese version of female sexual function index in a Chinese population-a pilot study[J]. J Sex Med, 2011, 8(4): 1101-1111. DOI: 10.1111/j.1743-6109.2010.02171.x.
[14] Liu H, Yu J, Chen Y, et al.Sexual function in cervical cancer patients: psychometric properties and performance of a Chinese version of the Female Sexual Function Index[J]. Eur J Oncol Nurs, 2016, 20(1): 24-30. DOI: 10.1016/j.ejon.2015.06.007.
[15] White ID, Tennant A, Taylor C.Sexual morbidity assessment in gyne-oncology follow-up: Development of the Sexual Well-Being After Cervical or Endometrial Cancer (SWELL-CE) patient-reported outcome measure[J]. J Sex Med, 2020, 17(10): 2005-2015. DOI: 10.1016/j.jsxm.2020.06.019.
[16] Jensen PT, Klee MC, Thranov I, et al.Validation of a questionnaire for self-assessment of sexual function and vaginal changes after gynaecological cancer[J].Psychooncol, 2004, 13(8): 577-592. DOI: 10.1002/pon.757.
[17] 宋丹, 刘玉慧, 周杰, 等. 妇科癌症治疗后性功能及阴道改变问卷的汉化及信效度评价[J]. 循证护理, 2022, 8(22): 3102-3105. DOI: 10.12102/j.issn.2095-8668.2022.22.021.
[18] Ferguson SE, Brotto LA, Kwon J, et al.Sexual health and quality of life in patients with low-risk early-stage cervical cancer: Results from GCIG/CCTG CX.5/SHAPE trial comparing simple versus radical hysterectomy[J]. J Clin Oncol, 2024: Jco2400440. DOI: 10.1200/JCO.24.00440.
[19] Kulkarni A, Sun G, Manuppelli S, et al.Sexual health and function among patients receiving systemic therapy for primary gynecologic cancers[J]. Gynecol Oncol, 2022, 165(2): 323-329. DOI: 10.1016/j.ygyno.2022.03.008.
[20] Paulsen A, Vistad I, Fegran L.Gynecological cancer survivors’ experiences with sexual health communication in nurse-led follow-up consultations[J]. Acta Obstet Gynecol Scand, 2024, 103(3): 551-560. DOI: 10.1111/aogs.14749.
[21] Bober SL, Krapf J. Overview of sexual dysfunction in female cancer survivors[EB/OL]. (2022-08-15). [2024-11-29]. https://office.sugh.net:9444/contents/overview-of-sexual-dysfunction-in-female-cancer-survivors.
[22] Pizetta LM, Reis AD, Mexas MP, et al.Management strategies for sexuality complaints after gynecologic cancer: a systematic review[J]. Revista Brasileira De Ginecologia E Obstetricia, 2022, 44(10):962-971.DOI:10.1055/s-0042-1756312.
[23] Duska LR. Overview of approach to cervical cancer survivors[EB/OL]. (2023-09-13)[2024-11-29]. https://office.sugh.net:9444/contents/overview-of-approach-to-cervical-cancer-survivors
[24] 张树燕, 阮璐璐, 吴珊珊. 基于PERMA理论的干预模式对宫颈癌患者同步放化疗预防阴道粘连和生活质量的影响[J].中国妇幼保健, 2022, 37(24): 4582-4586. DOI:10.19829/j.zgfybj.issn.1001-4411.2022.24.008.
[25] 赵亚楠, 路娜, 马喜梅, 等. 妇科恶性肿瘤患者化疗期间症状群的范围综述[J]. 中华护理杂志, 2022, 57(18): 2283-2288. DOI: 10.3761/j.issn.0254-1769.2022.18.017.
[26] Aquil A, El Kherchi O, El Azmaoui N, et al.Body image dissatisfaction and lower self-esteem as major predictors of poor sleep quality in gynecological cancer patients after surgery: cross-sectional study[J]. BMC Womens Health, 2021, 21(1): 229. DOI: 10.1186/s12905-021-01375-5.
[27] Buffart LM, Schreurs MAC, Abrahams HJG, et al.Effects and moderators of coping skills training on symptoms of depression and anxiety in patients with cancer: aggregate data and individual patient data Meta-analyses[J]. Clin Psychol Rev, 2020, 80: 101882. DOI: 10.1016/j.cpr.2020.101882.
[28] Doubova SV, Pérez-Cuevas R.Association of supportive care needs and quality of patient-centered cancer care with depression in women with breast and cervical cancer in Mexico[J]. Psychooncol, 2021, 30(4): 591-601. DOI: 10.1002/pon.5608.
[29] 刘媛媛, 刘高明, 胡进, 等. 子宫内膜癌治疗后外阴淋巴水肿患者症状体验与心理感受的质性研究[J].护理学报, 2022, 29(21): 1-5. DOI: 10.16460/j.issn1008-9969.2022.21.001.
[30] Roussin M, Lowe J, Hamilton A, et al.Sexual quality of life in young gynaecological cancer survivors: a qualitative study[J].Qual Life Res,2023,32(7):2107-2115.DOI:10.1007/s11136-023-03386-1.
[31] 陈效欣, 李颖菊, 孙涵菲, 等. 妇科癌症患者夫妻沟通质量量表的研制及信效度检验[J].中国实用护理杂志, 2023 (2):132-137.DOI:10.3760/cma.j.cn211501-20220115-00181.
[32] Abbott-Anderson K, Young PK, Eggenberger SK.Adjusting to sex and intimacy: gynecological cancer survivors share about their partner relationships[J]. J Women Aging, 2020,32(3):329-348.DOI:10.1080/08952841.2019.1591888.
[33] Roussin M, Lowe J, Hamilton A, et al.Factors of sexual quality of life in gynaecological cancers: a systematic literature review[J]. Arch Gynecol Obstet, 2021, 304(3): 791-805. DOI: 10.1007/s00404-021-06056-0.
[34] Paulsen A, Vistad I, Fegran L.Gynecological cancer survivors’ experiences with sexual health communication in nurse-led follow-up consultations[J]. Acta Obstet Gynecol Scand, 2024,103(3):551-560. DOI: 10.1111/aogs.14749.
[35] Bober SL, Michaud AL, Recklitis CJ.Finding sexual health aids after cancer: are cancer centers supporting survivors’ needs?[J]. J Cancer Surviv, 2019, 13(2): 224-230. DOI: 10.1007/s11764-019-00744-2.
[36] Lehmann V, Laan ETM,Den Oudsten BL.Sexual health-related care needs among young adult cancer patients and survivors: a systematic literature review[J]. J Cancer Surviv, 2022, 16(4): 913-924. DOI: 10.1007/s11764-021-01084-w.
[37] 罗然, 李贤富, 陈俊安, 等. 放疗对宫颈癌患者性生活质量的影响及处理研究进展[J]. 癌症进展, 2021, 19(16): 1628-1630. DOI: 10.11877/j.issn.1672-1535.2021.19.16.03.
[38] 石艳, 甘秀妮. 重庆市妇科医护人员对宫颈癌术后患者性问题管理的现状调查[J]. 中华护理杂志, 2020, 55(3): 427-432. DOI: 10.3761/j.issn.0254-1769.2020.03.022.
[39] Robison K, Kulkarni A, Dizon DS.Sexual health in women affected by gynecologic or breast cancer[J]. Obstet Gynecol, 2024, 143(4):499-514.DOI:10.1097/AOG.0000000000005506.
[40] Zhou Y, Rassy E, Coutte A, et al.Current standards in the management of early and locally advanced cervical cancer: update on the benefit of neoadjuvant/adjuvant strategies[J]. Cancers (Basel),2022,14(10):2449. DOI:10.3390/cancers14102449.
[41] 王耀苹, 佟玉静, 王坤. 普拉提联合盆底康复训练对青年宫颈癌根治术后尿失禁患者盆底肌张力及性功能的影响[J]. 中国康复, 2024, 39(5): 292-297. DOI: 10.3870/zgkf.2024.05.007.
[42] Huang L, Zhang J, Deng Y, et al.Niclosamide (NA) overcomes cisplatin resistance in human ovarian cancer[J]. Genes Dis, 2023, 10(4): 1687-1701. DOI:10.1016/j.gendis.2022.12.005.
[43] Whicker M, Black J, Altwerger G, et al.Management of sexuality, intimacy, and menopause symptoms in patients with ovarian cancer[J]. Am J Obstet Gynecol, 2017, 217(4): 395-403. DOI: 10.1016/j.ajog.2017.04.012.
[44] Winarto H, Ibrahim NAA, Putri YM, et al.Adjuvant chemoradiotherapy versus chemotherapy or radiotherapy in advanced endometrial cancer: a systematic review and meta-analysis[J]. PeerJ, 2022, 10: e14420. DOI: 10.7717/peerj.14420.
[45] Vilos GA, Reyes-Muñoz E, Riemma G, et al.Gynecological cancers and urinary dysfunction: a comparison between endometrial cancer and other gynecological malignancies[J]. Minerva Med, 2021,112(1):96-110. DOI: 10.23736/S0026-4806.20.06770-1.
[46] Cyr MP, Dumoulin C, Bessette P, et al.A prospective single-arm study evaluating the effects of a multimodal physical therapy intervention on psychosexual outcomes in women with dyspareunia after gynecologic cancer[J]. J Sex Med, 2021, 18(5): 946-954. DOI: 10.1016/j.jsxm.2021.02.014.
[47] Fan M, Wang Y, Zheng L, et al.Effectiveness of online mindfulness-based interventions for cancer patients: a systematic review and Meta-analysis[J]. Jpn J Clin Oncol, 2023, 53(11): 1068-1076. DOI: 10.1093/jjco/hyad101.
[48] Sopfe J, Pettigrew J, Afghahi A, et al.Interventions to improve sexual health in women living with and surviving cancer: Review and recommendations[J]. Cancers (Basel), 2021, 13(13):1-25. DOI: 10.3390/cancers13133153.
[49] 段乃娟, 孙丽, 李凤侠, 等. 基于二元应对的宫颈癌患者夫妻参与式绘画疗法干预方案构建研究[J]. 护理学报, 2024, 31(5): 7-11. DOI: 10.16460/j.issn1008-9969.2024.05.007.

基金

国家自然科学基金青年项目(81802612)

PDF(986 KB)

Accesses

Citation

Detail

段落导航
相关文章

/