护理学报 ›› 2023, Vol. 30 ›› Issue (3): 63-67.doi: 10.16460/j.issn1008-9969.2023.03.063
造血干细胞移植患者口腔护理管理的最佳证据总结
柴燕燕1, 李潇1, 刘宁2, 叶丽娟1, 曹建琼1
- 1.南方医科大学南方医院 血液科,广东 广州 510515;
2.遵义医科大学珠海校区 护理学系,广东 珠海 519041
摘要： 目的 总结成人造血干细胞移植患者口腔并发症预防及管理的最佳证据,为临床护理工作提供参考。方法 检索BMJ、UpToDate、JBI、NGC、NICE、医脉通、Cochrane Library、PubMed、Embase、CINAHL、Web of Science、中国知网、万方数据库,选取符合标准的文献。由2名研究员对文献进行质量评价,证据提取及整合。结果 共纳入证据19篇,包括指南8篇,临床决策1篇、证据总结4篇、专家共识4篇、随机对照试验2篇,从8个维度即评估、基础口腔护理、物理干预、营养干预、药物干预、症状管理、出院指导和人员支持,共总结16条最佳证据。结论 该研究总结造血干细胞移植患者口腔护理管理最佳证据,为临床医护人员开展口腔护理提供循证依据。医务人员应根据临床实际情况及患者意愿选择并应用最佳证据。
中图分类号:
- R473.55
| [1] 王昱, 黄晓军. 造血干细胞移植在血液疾病中的应用进展[J]. 中华血液学杂志, 2019, 40(8):704-708.DOI:10.3760/cma.j.issn.0253-2727.2019.08.020. [2] Elad S, Raber-Durlacher JE, Brennan MT, et al.Basic oral care for hematology-oncology patients and hematopoietic stem cell transplantation recipients: a position paper from the Joint Task Force of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) and the European Society for Blood and Marrow Transplantation (EBMT)[J]. Support Care Cancer, 2015,23(1):223-236.DOI:10.1007/s00520-014-2378-x. [3] 贾灵芝, 李小丽, 王凤然. 2015版“MASCC/ISOO/EBMT放化疗及造血干细胞移植者口腔护理专家共识”解读[J]. 护理研究, 2018, 32(2):167-168. DOI:10.3969/j.issn.1009-6493.2018.02.001. [4] Aromataris E, Fernandez R, Godfrey CM, et al.Summarizing systematic reviews: methodological development, conduct and reporting of an umbrella review approach[J]. Int J Evid Based Healthc,2015, 13(3):132-140.DOI:10.1097/xeb.0000000000000055. [5] Shea BJ, Reeves BC, Wells G, et al.AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both[J]. BMJ, 2017, 358:j4008. DOI:10.1136/bmj.j4008. [6] Brouwers MC, Kho ME, Browman GP, et al.AGREE II: advancing guideline development, reporting and evaluation in health care[J]. CMAJ, 2010, 182(18):E839-842.DOI:10.1503/cmaj.090449. [7] The Joanna Briggs Institute. JBI’s critical appraisal tools assist in assessing the trustworthiness, relevance and results of published papers[EB/OL]. (2017-11-24)[2020-06-13]. https://jbi.global/critical-appraisal-tools. [8] 刘云访, 喻姣花, 李素云, 等. ICU成人患者气管插管非计划性拔管预防及管理的证据总结[J]. 护理学报, 2020, 27(3):43-48. DOI:10.16460/j.issn1008-9969.2020.03.043. [9] 王春青, 胡雁. JBI证据预分级及证据推荐级别系统(2014版)[J]. 护士进修杂志, 2015, 30(11):964-967. [10] Peterson DE, Boers-Doets CB, Bensadoun RJ, et al.Management of oral and gastrointestinal mucosal injury: ESMO clinical practice guidelines for diagnosis, treatment, and follow-up[J]. Ann Oncol, 2015, 26(Suppl 5):v139-151. DOI:10.1093/annonc/mdv202. [11] Hong CHL, Gueiros LA, Fulton JS, et al.Systematic review of basic oral care for the management of oral mucositis in cancer patients and clinical practice guidelines[J]. Support Care Cancer, 2019, 27(10):3949-3967. DOI:10.1007/s00520-019-04848-4 [12] Navdeep K, Mary B,Anthony B,et al.The oral management of oncology patients requiring radiotherapy, chemotherapy and/or bone marrow transplantation[J].Faculty Dental Journal, 2019, 85:1-85. [13] Zadik Y, Arany PR, Fregnani ER, et al.Systematic review of photobiomodulation for the management of oral mucositis in cancer patients and clinical practice guidelines[J]. Support Care Cancer,2019,27(10):3969-3983.DOI:10.1007/s00520-019-04890-2. [14] Correa MEP, Cheng KKF, Chiang K, et al.Systematic review of oral cryotherapy for the management of oral mucositis in cancer patients and clinical practice guidelines[J]. Support Care Cancer, 2020, 28(5):2449-2456. DOI:10.1007/s00520-019-05217-x. [15] Elad S, Cheng KKF, Lalla RV, et al.MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy[J]. Cancer, 2020, 126(19): 4423-4431. DOI:10.1002/cncr.33100. [16] Logan RM, Al-Azri AR, Bossi P, et al.Systematic review of growth factors and cytokines for the management of oral mucositis in cancer patients and clinical practice guidelines[J]. Support Care Cancer, 2020, 28(5):2485-2498. DOI:10.1007/s00520-019-05170-9. [17] 马婷婷, 吴琼, 欧阳静, 等. 中国癌症症状管理实践指南—口腔黏膜炎[J]. 护士进修杂志, 2020, 35(Issue): 1871-1878. DOI:10.16821/j.cnki.hsjx.2020.25.028. [18] Robert SN,Joseph AT.Oral toxicity associated with chemotherapy[EB/OL]. (2021-06-04)[2021-06-22]. http://uptodate.0005.a.isus.top/contents/oral-toxicity-associated-with-chemotherapy?search=Oral%20toxicity%20associated%20with%20chemotherapy&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1. [19] Supportive Palliative Care Editorial Board. Oral complications of chemotherapy and head/neck radiation (PDQ®): health professional version[M]. Bethesda: National Cancer Institute, 2016. [20] Whitehorn A. Oral mucositis: assessment [EB/OL]. (2021-04-06)[2021-05-24].http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=jbi&NEWS=N&AN=JBI15067. [21] Whitehorn A. Oral mucositis: prevention and management principles [EB/OL].(2021-04-09)[2021-05-24].http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=jbi&NEWS=N&AN=JBI966. [22] Lizarondo L. Hematopoietic stem cell transplantation: oral care [EB/OL].(2021-05-04)[2021-05-24].http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=jbi&NEWS=N&AN=JBI110772. [23] Botti S,Cecco V,Galgano L, et al.Oral mucositis in hematopoietic stem cell transplantation (HSCT): position statement by Gruppo Italiano Trapianto Di Midollo Osseo(GITMO) Nurses Group[J]. Drug and Cell Therapy in Hematology, 2014, 4:205-223. [24] 中华医学会放射肿瘤治疗学分会. 放射性口腔黏膜炎防治策略专家共识(2019)[J]. 中华放射肿瘤学杂志, 2019,28(9):641-647. DOI:10.3760/cma.j.issn.1004-4221.2019.09.001. [25] 中国临床肿瘤学会抗肿瘤药物安全管理专家委员会, 中国临床肿瘤学会肿瘤支持与康复治疗专家委员会. 抗肿瘤治疗引起急性口腔黏膜炎的诊断和防治专家共识[J]. 临床肿瘤学杂志,2021,26(5):449-459. DOI:10.3969/j.issn.1009-0460.2021.05.011. [26] Hosseinjani H, Hadjibabaie M, Gholami K, et al.The efficacy of erythropoietin mouthwash in prevention of oral mucositis in patients undergoing autologous hematopoietic SCT: a double-blind, randomized, placebo-controlled trial[J]. Hematol Oncol,2017,35(1):106-112.DOI:10.1002/hon.2250. [27] Salvador DRN, Soave DF, Sacono NT, et al.Effect of photobiomodulation therapy on reducing the chemo-induced oral mucositis severity and on salivary levels of CXCL8/interleukin 8, nitrite, and myeloperoxidase in patients undergoing hematopoietic stem cell transplantation: a randomized clinical trial[J]. Lasers Med Sci, 2017, 32(8): 1801-1810. DOI:10.1007/s10103-017-2263-1. [28] Keefe DM, Schubert MM, Elting LS, et al.Updated clinical practice guidelines for the prevention and treatment of mucositis[J]. Cancer, 2007, 109(5):820-831. DOI:10.1002/cncr.22484. [29] Hensley ML, Hagerty KL, Kewalramani T, et al.American Society of Clinical Oncology 2008 clinical practice guideline update: use of chemotherapy and radiation therapy protectants[J]. J Clin Oncol, 2009, 27(1):127-145. DOI:10.1200/jco.2008.17.2627. [30] Lalla RV, Bowen J, Barasch A, et al.MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy[J]. Cancer, 2014, 120(10): 1453-1461. DOI:10.1002/cncr.28592. [31] Hong CH, Napeñas J J, Hodgson BD, et al.A systematic review of dental disease in patients undergoing cancer therapy[J]. Support Care Cancer, 2010, 18(8):1007-1021. DOI:10.1007/s00520-010-0873-2. [32] Worthington HV, Clarkson JE, Bryan G, et al. Interventions for preventing oral mucositis for patients with cancer receiving treatment[J].Cochrane Database Syst Rev, 2010, 12(4): Cd000978. DOI:10.1002/14651858.CD000978.pub3. [33] Riley P, Glenny AM, Worthington HV, et al. Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors[J]. Cochrane Database Syst Rev, 2017, 11(11):Cd011990. DOI:10.1002/14651858.CD011990.pub2. [34] Mori T, Yamazaki R, Aisa Y, et al.Brief oral cryotherapy for the prevention of high-dose melphalan-induced stomatitis in allogeneic hematopoietic stem cell transplant recipients[J]. Support Care Cancer, 2006, 14(4):392-395. DOI:10.1007/s00520-005-0016-3. |
| [1] | 张静, 彭焕椽, 陈佳, 鲁永锦, 刘克玄, 侯晓敏. 成人体外循环心脏手术患者预防手术部位感染的最佳证据总结[J]. 护理学报, 2025, 32(4): 41-47. |
| [2] | 李若雨, 刘鑫, 林萍, 陈丹, 林桦. 出院患者用药安全管理的最佳证据总结[J]. 护理学报, 2025, 32(3): 50-55. |
| [3] | 杨小娟, 毛孝容, 王静, 江华, 李蓉, 樊宇, 文青, 李林章, 陈晓容. 成人重度烧伤患者早期肠内营养管理的最佳证据总结[J]. 护理学报, 2025, 32(3): 56-61. |
| [4] | 刘硕怡, 熊莉娟, 李凌, 王玉梅, 何嘉, 李鑫, 袁淑蕾, 郭雪琴, 王暘婧, 张慧娟. 老年住院患者衰弱预防及管理临床实践指南的质量评价及内容分析[J]. 护理学报, 2025, 32(2): 50-55. |
| [5] | 闫亚铃, 乐美妮, 姚桃琴, 王雪莲, 姜建玲, 辛艺. 老年胃肠肿瘤患者围手术期衰弱管理方案的构建[J]. 护理学报, 2025, 32(2): 74-78. |
| [6] | 陈洁, 孟庆童, 刘惊今, 吴艳妮. 基于指南的慢性心力衰竭患者运动康复科普手册研制[J]. 护理学报, 2024, 31(9): 36-41. |
| [7] | 符路路, 解艺璇, 王玥, 魏巍, 张传英, 朱宇. 新生儿操作性疼痛听觉刺激干预的证据总结[J]. 护理学报, 2024, 31(9): 42-47. |
| [8] | 纪锐婷, 林丹娜, 刘小成, 李婷婷, 谢映梅, 胡冰, 应文娟. 早产儿初乳口腔免疫疗法的最佳证据总结[J]. 护理学报, 2024, 31(8): 37-42. |
| [9] | 张小莉, 杨鑫玉, 肖宇, 刘春燕, 张璐, 伍晓琴, 黄月霖, 傅静. 晚期癌症患者代理决策者安宁疗护决策后悔研究的范围综述[J]. 护理学报, 2024, 31(8): 49-54. |
| [10] | 周毅峰, 杨继平, 胡正中, 袁浩. 肝癌切除手术患者目标导向性血糖监测的证据总结[J]. 护理学报, 2024, 31(7): 46-50. |
| [11] | 莫选菊, 吴远, 张曼, 刘章来, 申铁梅. 共患慢性失眠症住院患者实施睡眠限制疗法的证据总结[J]. 护理学报, 2024, 31(6): 62-66. |
| [12] | 文昶, 徐志辉, 郭倩, 杨栋, 王莉. Jeffries模拟教学模式在口腔护理教学中的实践[J]. 护理学报, 2024, 31(4): 17-20. |
| [13] | 杨建国, 何细飞, 鄢建军, 张梦, 杨纯子, 徐蓉, 王艳芳. 局部枸橼酸抗凝在连续性肾脏替代治疗中的应用及管理的最佳证据总结[J]. 护理学报, 2024, 31(4): 48-53. |
| [14] | 刘璇, 蓝玉清, 李梦如, 王小惠, 钟雪梅, 周文. 住院老年性痴呆患者跌倒预防的最佳证据总结[J]. 护理学报, 2024, 31(4): 54-59. |
| [15] | 祁水林, 林桦, 邓锐颖, 李荣杰, 李若雨, 王凤廷. 老年皮肤瘙痒症患者非药物管理的最佳证据总结[J]. 护理学报, 2024, 31(3): 46-50. |
|
||