目的 检索并总结肝癌切除手术患者目标导向性血糖监测相关证据,为临床提供指导依据。方法 应用PICO程式结构化临床问题,检索中国指南网,美国指南网,英国国家临床医学研究所指南库,国际指南图书馆,英格兰学院间指南网,UpToDate,BMJ,Cochrane Library,PubMed,Web of Science,EMbase,CINAHL,中国生物医学数据库,中国知网,万方医学数据库。采用相关评价工具对纳入的文献进行质量评价。结果 共纳入文献15篇,包括指南6篇,专家共识3篇,原始研究6篇,总结出18条审查指标,包括多学科团队构建、术前评估及健康教育、监测方法、术前/术中/术后目标导向性血糖监测措施、异常血糖处理、术后交接及管理等内容。结论 本研究总结了肝癌切除手术患者目标导向性血糖监测的最佳证据,为规范临床血糖监测及控制,降低血糖异常事件及并发症发生率,加速术后康复提供循证依据。
Abstract
Objective To search and summarize the evidence for target-oriented blood glucose monitoring in patients undergoing hepatocellular carcinoma resection, and to provide guidance for clinical practice. Methods We applied PICO framework to structure clinical questions, and searched literature in databases of Chinese guidelines, American guidelines, UK National Institute of Clinical Medicine guidelines, International Guidelines Library, England inter-college guidelines, UpToDate, BMJ, Cochrane Library, PubMed, Web of Science, EMbase, CINAHL, China Biomedical Database, China National Knowledge Network, Wanfang Medical Database. Related evaluation tools were used to evaluate the quality of the included literature. Results A total of 15 pieces of literature were collected, including 6 guidelines, 3 expert consensus and 6 similar experimental studies. Eighteen review indicators were summarized, including team building, preoperative evaluation and health education, preoperative/intraoperative/postoperative target-oriented blood glucose monitoring measures, abnormal blood glucose management, postoperative handover and management, etc. Conclusion This study summarizes the best evidence for target-oriented blood glucose monitoring in patients undergoing hepatocellular carcinoma resection, providing evidence-based evidence for reducing the incidence of abnormal blood glucose events and complications and accelerating postoperative rehabilitation.
关键词
肝癌手术 /
目标导向 /
血糖监测 /
围术期 /
循证护理
Key words
hepatocellular carcinoma resection /
target-oriented /
blood glucose monitoring /
perioperative /
evidence-based nursing
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] Niu X, Liu Jg, Feng ZD, et al.Short-term efficacy of precise hepatectomy and traditional hepatectomy for primary liver cancer: a systematic review and Meta-analysis[J]. J Gastrointest Oncol, 2021, 12(6):3022-3032. DOI: 10.21037/jgo-21-735.
[2] Dougherty SM, Schommer J, Salinas JL, et al.Immediate preoperative hyperglycemia correlates with complications in non-cardiac surgical cases[J].J Clin Anesth,2021,74:110375. DOI: 10.1016/j.jclinane.2021.110375.
[3] Stras WA, Wasiak D, Lągiewska B, et al. Recurrence of hepatocellular carcinoma after liver transplantation: risk factors and predictive models[J]. Ann Transpl, 2022, 27:e934924. DOI: 10.12659/AOT.934924.
[4] Kim S, Park J, Kim H, et al.Intraoperative hyperglycemia may be associated with an increased risk of myocardial injury after non-cardiac surgery in diabetic patients[J]. J Clin Med, 2021, 10(22). DOI: 10.3390/jcm10225219.
[5] 吴永红, 朱艳萍, 周艳. 目标导向血糖监测方案在多发伤患者血糖调控中的应用研究[J]. 护士进修杂志, 2015, 30(23):2137-2140. DOI: 10.16821/j.cnki.hsjx.2015.23.008.
[6] 胡雁, 郝玉芳. 循证护理学[M]. 2版. 北京: 人民卫生出版社, 2018:28-35.
[7] Dicenso A, Bayley L, Haynes RB.Accessing pre-appraised evidence: fine-tuning the 5S model into a 6S model[J]. Evid Based Nurs,2009,12(4):99-101.DOI:10.1136/ebn.12.4.99-b.
[8] Brouwers MC, Kho ME, Browman GP, et al.AGREE II: advancing guideline development, reporting and evaluation in health care[J]. J Clin Epidemiol, 2010, 63(12):1308-1311. DOI: 10.1016/j.jclinepi.2010.08.005.
[9] 张方圆, 沈傲梅, 曾宪涛, 等. 系统评价方法学质量评价工具 AMSTAR 2 解读[J]. 中国循证心血管医学杂志, 2018, 10(1):14-18. DOI: 1674-4055(2018)01-0014-05.
[10] The Joanna Briggs Institute. JBI's critical appraisal tools assist in assessing the trustworthiness, relevance and results of published papers[EB/OL]. (2017-11-24) [2020-06-13]. https://jbi.global/critical-appraisal-tools.
[11] 王春青,胡雁. JBI 证据预分级及证据推荐级别系统(2014版)[J]. 护士进修杂志, 2015,30(11):964-967. DOI: 1002-6975(2015)11-0964-04.
[12] Joint British Diabetes Societies Inpatient Care Group. Guideline for perioperative care for people with diabetes mellitus undergoing elective and emergency surgery.[EB/OL]. (2021-03-10). https://www.JBDS-IP.cn/guideline/show_article.
[13] Australian Diabetes Society.Peri-operative diabetes management guidelines[EB/OL]. [2020-08-29].https://www.docin.com/p-395149843.html.
[14] Wang J, Chen K, Chen Y, et al.Chinese clinical practice guideline for perioperative blood glucose management[J]. Diabetes Metab Res, 2021,37(7):e3439. DOI:10.1002/dmrr.3439.
[15] Bao YQ, Zhu DL.Clinical application guidelines for blood glucose monitoring in China (2022 edition)[J]. Diabetes-Metab Res, 2022, 38(8):e3581. DOI: 10.1002/dmrr.3581.
[16] Joliat GR, Kobayashi K, Hasegawa K, et al.Guidelines for perioperative care for liver surgery: Enhanced Recovery After Surgery (ERAS) Society recommendations 2022[J]. World J Surg,2023,47(1):11-34.DOI:10.1007/s00268-022-06732-5.
[17] 中华医学会外科学分会, 中华医学会麻醉学分会. 中国加速康复外科临床实践指南(2021)(肝胆部分)[J]. 协和医学杂志, 2021, 12(5):632-640. DOI: 10.12290/xhyxzz.20210002.
[18] 陈莉明, 陈伟, 陈燕燕, 等. 成人围手术期血糖监测专家共识[J]. 中国糖尿病杂志,2021,29(2):81-85.DOI:10.3969/j.issn.1006-6187.2021.02.001.
[19] Vogt AP, Bally L.Perioperative glucose management: current status and future directions[J]. Best Prac Res Clin Anaesthesiol, 2020, 34(2):213-224. https://doi.org/10.1016/j.bpa.2020.04.015.
[20] Duggan E, Chen Y.Glycemic management in the operating room: screening, monitoring, oral hypoglycemics, and insulin therapy[J]. Curr Diabetes Rep, 2019, 19(11):134. DOI: 10.1007/s11892-019-1277-4.
[21] Blixt C, Larsson M, Isaksson B, et al.The effect of glucose control in liver surgery on glucose kinetics and insulin resistance[J]. Clin Nutr, 2021, 40(7):4526-4534. https://doi.org/10.1016/j.clnu.2021.05.017.
[22] Gen L, Dietz CJK, Freundlich RE, et al.The impact of an intraoperative clinical decision support tool to optimize perioperative glycemic management[J]. J Med Syst, 2020, 44(10):175. DOI: 10.1007/s10916-020-01643-1.
[23] 吕素珍, 黄旭芳, 毛剑婷, 等. 强化血糖管理在肝癌合并糖尿病患者射频消融围手术期的应用研究[J]. 介入放射学杂志, 2019, 28(6):582-585. DOI: 10.3969/j.issn.1008-794X.2019.06.018.
[24] Cammu G, Vermeiren K, Lecomte P, et al.Perioperative blood glucose management in patients undergoing tumor hepatectomy[J]. J Clin Anesth, 2009, 21(5):329-335. DOI: 10.1016/j.jclinane.2008.09.006.
[25] Mendez CE, Walker RJ, Dawson AZ, et al.Using a diabetes risk score to identify patients without diabetes at risk for new hyperglycemia in the hospital[J]. Endocr Pract, 2021, 27(8):807-812. DOI: 10.1016/j.eprac.2021.04.003.
[26] 丁佑铭, 张爱民, 姚峰, 等. ICGR15和OGTT预测肝癌患者肝脏储备功能的价值[J]. 中国普通外科杂志, 2001, 10(2):162-165.DOI:10.3969/j.issn.1005-6947.2001.02.020.
基金
2023年湖南省自然科学基金课题(2023JJ60315,2023JJ60313)