以质量求发展,以服务铸品牌

护理学报 ›› 2020, Vol. 27 ›› Issue (16): 28-34.doi: 10.16460/j.issn1008-9969.2020.16.028

• 循证护理 • 上一篇    下一篇

成人结肠镜检查前肠道准备的最佳证据总结

林俏, 张广清, 刘梅娟, 黄颖, 刘丹阳, 刘玉萍, 邢同印, 陈继华   

  1. 南方医科大学南方医院,广东 广州 510515
  • 收稿日期:2020-02-21 出版日期:2020-08-25 发布日期:2020-09-11
  • 通讯作者: 张广清(1966-),女,湖南湘潭人,本科学历,硕士研究生导师,主任护师。E-mail:hlbzhang@sina.com
  • 作者简介:林俏(1987-),女,山东新泰人,本科学历,硕士研究生在读,护师。
  • 基金资助:
    南方医院护理创优-循征护理项目(2018EBNe018)

Best Evidence Summary for Bowel Preparation Before Colonoscopy in Adults

LIN Qiao, ZHANG Guang-qing, LIU Mei-juan, HUANG Ying, LIU Dan-yang, LIU Yu-ping, XING Tong-yin, CHEN Ji-hua   

  1. Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
  • Received:2020-02-21 Online:2020-08-25 Published:2020-09-11

摘要: 目的 检索分析并总结成人结肠镜检查前肠道准备的相关证据,为临床护理人员、管理者对结肠镜检查的患者进行最佳的肠道准备提供科学依据,同时也为患者及家属提供参考依据。方法 应用循证的方法,针对成人结肠镜检查前的肠道准备提出问题,并检索近5年内的相关研究,包括指南、临床决策、证据总结(evidence summary,ES)、最佳实践信息册(best practice Information sheet,BPIS)、推荐实践(recommendation practice,RP)、系统评价(systematic review,SR),检索数据库依次为:Up To Date、BMJ Best Practice、英国国家卫生与临床优化研究所指南网(National Institute for Health and Care Excellence, NICE)、澳大利亚JBI循证卫生保健中心证据总结数据库、Cochrane数据库、医脉通指南网、PubMed、CINAHL数据库、中国知网。采用英国2009年更新的《临床指南研究与评价系统》(Appraisal of Guidelines for Research and Evaluation Instrument Ⅱ, AGREEⅡ)、JBI的文献质量评价工具对各类研究进行文献质量评价及证据级别评定。结果 最终纳入10篇文献,其中临床决策2篇,指南4篇,证据总结2篇,系统评价2篇。结合临床护理人员的判断,汇总出17条结肠镜检查前肠道准备的证据,包括肠道准备的宣教、饮食指导、用药时机、肠道清洁剂的选择及服用方法、辅助药物及特殊患者的肠道准备等方面。结论 最佳的肠道准备方案仍需要根据医疗机构的实际条件、医护人员的临床经验及患者需求相结合来共同制定。

关键词: 结肠镜检查, 肠道准备, 肠道清洁度, 循证护理, 最佳证据

Abstract: Objective To retrieve, analyze and summarize available evidence on bowel preparation before colonoscopy in adults, and to provide reference for clinical nurses to carry out standardized bowel preparation. Methods Nursing problems of bowel preparation before colonoscopy in adults were raised using evidence-based method, and related studies of bowel preparation before colonoscopy in the past 5 years were searched. Database retrieved were as follows: Up To Date, BMJ Best Practice,National Institute for Health and Clinical Excellence (NICE), Australia based health care center syndrome (JBI) evidence summary database, Cochrane database, medical pulse flux, PubMed, CINAHL database and CNKI. The quality and grade of various studies were evaluated using the 2012 updated clinical guidelines research and evaluation system (AGREE Ⅱ) and the literature quality evaluation tool of JBI. Results Ten articles were enrolled, including 2 clinical decisions, 4 guidelines, 2 evidence summaries, and 2 systematic reviews. Totally 17 pieces of evidence for bowel preparation before colonoscopy in adults including health education, dietary guidance, timing of preparation, choice and use of laxatives, adjunctive drugs and bowel preparation for special patients were collected. Conclusion It is still necessary to combine the actual conditions of the medical institution, clinical experience of the medical staff and the needs of the patients to develop the best bowel preparation solutions.

Key words: colonoscopy, bowel preparation, satisfactory of colon-cleaning, evidence-based nursing, best evidence

中图分类号: 

  • R473.57
[1] 郭天安,谢丽,赵江,等. 中国结直肠癌1988-2009年发病率和死亡率趋势分析[J]. 中华胃肠外科杂志,2018,21(1):33-40. DOI:10.3760/cma.j.issn.1671-0274.2018.01.007.
[2] Zhang L, Cao F, Zhang G,et al.Trends in and Predictions of Colorectal Cancer Incidence and Mortality in China from 1990 to 2025[J]. Front Oncol, 2019, 9:98. DOI:10.3389/fonc.2019.00098.
[3] Chen W, Zheng R, Baade PD, et al.Cancer Statistics in China, 2015[J]. CA Cancer J Clin, 2016, 66(2):115-132. DOI:10.3322/caac.21338.
[4] 郑荣寿,孙可欣,张思维,等. 2015年中国恶性肿瘤流行情况分析[J].中华肿瘤杂志,2019,41(1):19-28. DOI:10.3760/cma.j.issn.0253-3766.2019.01.005.
[5] Rongshou Z, Hongmei Z, Siwei Z, et al.National Estimates of Cancer Prevalence in China, 2011[J]. Cancer Lett, 2016, 370(1):33-38. DOI:10.1016/j.canlet.2015.10.003.
[6] 李兆申,金震东,令狐恩强. 中国早期结直肠癌筛查流程专家共识意见(2019,上海)[J]. 中华内科杂志, 2019, 58(10): 736-744. DOI:10.3760/cma.j.issn.0578-1426.2019.10.004.
[7] Allemani C, Matsuda T, Di Carlo V, et al.Global Surveillance of Trends in Cancer Survival 2000-14(CONCORD-3): Analysis of Individual Records for 37513025 Patients Diagnosed with One of 18 Cancers from 322 Population-based Registries in 71 Countries[J].Lancet,2018,391(10125):1023-1075. DOI:10.1016/S0140-6736(17)33326-3.
[8] Sankaranarayanan R, Swaminathan R, Brenner H,et al.Cancer Survival in Africa, Asia, and Central America: A Population-Based Study[J]. Lancet Oncol, 2010,11(2):165-173. DOI:10.1016/S1470-2045(09)70335-3.
[9] 柏愚,杨帆,马丹,等. 中国早期结直肠癌筛查及内镜诊治指南(2014年,北京)[J]. 胃肠病学, 2015, 20(6):345-365. DOI: 10.3969/j.issn.1008-7125.2015.06.006.
[10] Froehlich F, Wietlisbach V, Gonvers J, et al.Impact of Colonic Cleansing on Quality and Diagnostic Yield of Colonoscopy: The European Panel of Appropriateness of Gastrointestinal Endoscopy European Multicenter Study[J]. Gastrointest Endosc, 2005, 61(3):378-384. DOI:10.1016/S0016-5107(04)02776-2.
[11] Menees SB, Kim HM, Elliott EE, et al.The Impact of Fair Colonoscopy Preparation on Colonoscopy Use and Adenoma Miss Rates in Patients Undergoing Outpatient Colonoscopy[J]. Gastrointest Endosc, 2013, 78(3):510-516. DOI:10.1016/j.gie.2013.03.1334.
[12] 朱政,胡雁,邢唯杰,等.不同类型循证问题的构成[J].护士进修杂志,2017,32(21):1991-1994.DOI:10.16821/j.cnki.hsjx.2017.21.025.
[13] Brouwers MC, Kho ME, Browman GP, et al.AGREE II: Advancing Guideline Development, Reporting and Evaluation in Health Care[J]. CMAJ, 2010,182(18):E839-E842. DOI:10.1503/cmaj.090449.
[14] 顾莺,张慧文,周英凤,等. JBI循证卫生保健中心关于不同类型研究的质量评价工具——系统评价的方法学质量评价[J]. 护士进修杂志, 2018, 33(8):701-703. DOI:10.16821/j.cnki.hsjx.2018.08.008.
[15] 王春青,胡雁. JBI证据预分级及证据推荐级别系统(2014版)[J].护士进修杂志,2015,30(11):964-967.DOI:10.16821/j.cnki.hsjx.2015.11.002.
[16] A-Rahim Y,Falchuk M.Bowel Preparation before Colonoscopy in Adults[EB/OL].(2020-02-10). http://uptodate.0007.isjp.top/contents/bowel-preparation-before-colonoscopy-in-adults?search=Bowel%20preparation%20before%20colonos-copy%20in%20adults&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1.
[17] Strate L. Approach to Acute Lower Gastrointestinal Bleeding in Adults [EB/OL].(2020-02-10). http://uptodate.0007.isjp.top/contents/approach-to-acute-lower-gastrointestinal-bleeding-in-adults?search=Approach%20to%20acute%20lower%20gastrointestinal%20bleeding%20in%20adults&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1.
[18] Hassan C, East J, Radaelli F, et al.Bowel Preparation for Colonoscopy:European Society of Gastrointestinal Endoscopy (ESGE) Guideline-Update 2019[J].Endoscopy,2019,51(8):775-794.DOI: https://doi.org/10.1055/a-0959-0505.
[19] Committee ASOP.Bowel Preparation before Colonoscopy[J]. Gastrointest Endosc, 2015, 81(4):781-794. DOI:10.1016/j.gie.2014.09.048.
[20] Johnson D, Barkun A, Cohen L, et al.Optimizing Adequacy of Bowel Cleansing for Colonoscopy:Recommendations from the US Multi-society Task Force on Colorectal Cancer[J]. Gastroenterology, 2014,147(4):903-924.DOI:10.1053/j.gastro.2014.07.002.
[21] 李兆申,令狐恩强. 中国消化内镜诊疗相关肠道准备指南(2019,上海)[J]. 中华内科杂志, 2019, 58(7):485-495. DOI:10.3760/cma.j.issn.0578-1426.2019.07.002.
[22] Lauren D. The Joanna Briggs Institute EBP Database Evidence Summary. Colonoscopy: Bowel Preparation[EB/OL]. [2019-12-04](2020-02-10). http://connect.jbiconnectplus.org/Search.aspx
[23] Priyanka P. The Joanna Briggs Institute EBP Database Evidence Summary.Colonoscopy:Bowel Preparation (Low Residue Diet)[EB/OL].[2019-05-23] (2020-02-10). http://connect.jbiconnectplus.org/Search.aspx
[24] Kurlander J.E, Sondhi A. R, Waljee A. K, et al. How Efficacious Are Patient Education Interventions to Improve Bowel Preparation for Colonoscopy? A Systematic Review[J].PloS one, 2016, 11(10).DOI:10.1371/journal.pone.0164442.
[25] Rocha RSP, Ribeiro IB, de Moura DTH, et al. Sodium Picosulphate or Polyethylene Glycol before Elective Colonoscopy in Outpatients? A Systematic Review and Meta-Analysis[J].World J Gastrointest Endosc, 2018,10(12):422-441. DOI10.4253/wjge.v10.i12.422.
[26] Wang SL, Wang Q, Yao J, et al.Effect of WeChat and Short Message Sservice on Bowel Preparation:An Endoscopist Blinded,Randomized Controlled Trial[J].Eur J Gastroenterol Hepatol,2019, 31(2):170-177.DOI:10.1097/MEG.0000000000001303.
[27] Kang X, Zhao L, Leung F, et al. Delivery of Instructions via Mobile Social Media App Increases Quality of Bowel Preparation[J]. Clin Gastroenterol Hepatol, 2016, 14(3):429-435.e3. DOI:10.1016/j.cgh.2015.09.038.
[28] Gimeno-Garcia AZ, de la Barreda Heuser R, Reygosa C, et al. Impact of a 1-day Versus 3-day Low-Residue Diet on Bowel Cleansing Quality Before Colonoscopy:A Randomized Controlled Trial[J]. Endoscopy,2019,51(7):628-636. DOI: 10.1055/a-0864-1942.
[29] Shah H, Desai D, Samant H, et al.Comparison of Split-dosing vs. Non-split (Morning) Dosing Regimen for Assessment of Quality of Bowel Preparation for Colonoscopy[J].World J Gastrointest Endosc,2014, 6(12):606-611.DOI:10.4253/wjge.v6.i12.606.
[30] Kotwal VS, Attar BM, Carballo MD, et al.Morning-only Polyethylene Glycol Is Noninferior but Less Preferred by Hospitalized Patients as Compared with Split-dose Bowel Preparation[J]. J Clin Gastroenterol,2014,48(5):414-418. DOI:10.1097/MCG.0b013e31829f30e9.
[31] Chan WK, Azmi N, Mahadeva S, et al.Split-Dose vs. Same-day Reduced-volume Polyethylene Glycol Electrolyte Lavage Solution for Morning Colonoscopy[J]. World J Gastroenterol, 2014, 20(39):14488-14494.DOI:10.3748/wjg.v20.i39.14488.
[32] Siddiqui AA, Yang K, Spechler SJ,et al.Duration of the Interval Between the Completion of Bowel Preparation and the Start of Colonoscopy Predicts Bowel-preparation Quality[J]. Gastrointest Endosc,2009,69(3 Pt 2):700-706. DOI:10.1016/j.gie.2008.09.047.
[33] Seo EH, Kim TO, Park MJ, et al.Optimal Preparation-to-colonoscopy Interval in Split-dose PEG Bowel Preparation Determines Satisfactory Bowel Preparation Quality: An Observational Prospective Study[J].Gastrointest Endosc, 2012,75(3):583-590. DOI:10.1016/j.gie.2011.09.029.
[34] Bucci C, Rotondano G, Hassan C, et al. Optimal Bowel Cleansing for Colonoscopy:Split the Dose!A Series of Meta-analyses of Controlled Studies[J].Gastrointest Endosc, 2014,80(4):566-576.e2. DOI:10.1016/j.gie.2014.05.320.
[35] Zhang S, Li M, Zhao Y, et al.3-L Split Dose Is Superior to 2-L Polyethylene Glycol in Bowel Cleansing in Chinese Population: A Multicenter Randomized, Controlled Trial[J].Medicine, 2015,94(4):e472.DOI:10.1097/MD. 0000000000000472.
[36] Kang X, Zhao L, Zhu Z, et al.Same-Day Single Dose of 2 Liter Polyethylene Glycol is Not Inferior to the Standard Bowel Preparation Regimen in Low-risk Patients: A Randomized, Controlled trial[J]. Am J Gastroenterol, 2018,113(4):601-610.DOI:10.1038/ajg.2018.25.
[37] Du YQ, Yuan YZ,Ge ZZ,et al.Comparison of Bowel Preparation Quality with A Bowel Purgative Containing Sodium Picosulfate, Magnesium Oxide and Citric Acid versus A PEG-ELS Solution: A Prospective RCT in China Using Chinese language Validated Ottawa Scale[J]. Gastrointest Endosc, 2012, 75(4):AB286.DOI:10.1016/j.gie.2012.03.728.
[38] Tan JJY, Tjandra JJ.Which Is the Optimal Bowel Preparation for Colonoscopy—A Meta-analysis[J]. Colorectal Dis,2006,8(4):247-258.DOI:10.1111/j.1463-1318.2006.00970.x.
[39] Jin Z, Lu Y, Zhou Y, et al.Systematic Review and Meta-Analysis:Sodium Picosulfate/Magnesium Citrate vs. Polyethylene Glycol for Colonoscopy Preparation[J]. Eur J Clin Pharmacol,2016,72(5):523-532. DOI:10.1007/s00228-016-2013-5.
[40] Lieshout IV, Munsterman ID, Eskes AM, et al.Systematic Review and Meta-analysis:Sodium Picosulphate with Magnesium Citrate as Bowel Preparation for Colonoscopy[J]. United European Gastroenterol J,2017, 5(7):917-943. DOI: 10.1177/2050640616684696.
[41] Rejchrt S, Bures J, Siroky M, et al.A Prospective, Observational Study of Colonic Mucosal Abnormalities Associated with Orally Administered Sodium Phosphate for Colon Cleansing before Colonoscopy[J].Gastrointest Endosc,2004,59(6):651-654. DOI:10.1016/s0016-5107(04)00158-0.
[42] Lawrance IC, Willert RP, Murray K.Bowel Cleansing for Colonoscopy: Prospective Randomized Assessment of Efficacy and of Induced Mucosal Abnormality with Three Preparation Agents[J].Endoscopy,2011,43(5):412-418.DOI: 10.1055/s-0030-1256193.
[43] Zwas FR, Cirillo NW, el-Serag HB, et al. Colonic Mucosal Abnormalities Associated with Oral Sodium Phosphate Solution[J]. Gastrointest Endosc,1996,43(5):463-466. DOI: 10.1016/s0016-5107(96)70286-9.
[44] Kim ES, Kim KO, Jang BI, et al.Crohn’s and Colitis Association in Daegu-gyeongbuk (CCAiD). Comparison of 4-L Polyethylene Glycol and 2-L Polyethylene Glycol Plus Ascorbic Acid in Patients with Inactive Ulcerative Colitis[J]. Dig Dis Sci, 2017,62(9):2489-2497. DOI:10.1007/s10620-017-4634-7.
[45] Manes G, Fontana P, de Nucci G, et al. Colon Cleansing for Colonoscopy in Patients with Ulcerative Colitis: Efficacy and Acceptability of a 2-L PEG Plus Bisacodyl Versus 4-L PEG[J]. Inflamm Bowel Dis,2015,21(9):2137-2144.DOI: 10.1097/MIB.0000000000000463.
[46] Restellini S, Kherad O, Bessissow T, et al.Systematic Review and Meta-analysis of Colon Cleansing Preparations in Patients with Inflammatory Bowel Disease[J].World J Gastroenterol, 2017, 23(32):5994-6002.DOI:10.3748/wjg.v23.i32.5994.
[47] Jensen DM, Machicado GA.Diagnosis and Treatment of Severe Hematochezia. The Role of Urgent Colonoscopy After Purge[J]. Gastroenterology,1988,95(6):1569-1574. DOI:10.1016/s0016-5085(88)80079-9.
[48] Saito K, Inamori M, Sekino Y, et al.Management of Acute Lower Intestinal Bleeding: What Bowel Preparation Should be Required for Urgent Colonoscopy?[J]. Hepatogastroenterology,2009,56(94/95):1331-1334.
[49] Lim DS, Kim HG, Jeon SR, et al.Comparison of Clinical Effectiveness of the Emergent Colonoscopy in Patients with Hematochezia According to the Type of Bowel Preparation[J]. J Gastroenterol Hepatol, 2013,28(11):1733-1737. DOI: 10.1111/jgh.12264.
[50] 秦榕,高建鹏,尧颖,等. 下消化道出血患者经不同肠道准备后急诊肠镜检查的效果比较[J]. 中华消化内镜杂志,2018, 35(3):212-214.DOI:10.3760/cma. j. issn.1007-5232.2018.03.016.
[51] 孙畅,何文英,王策,等. 住院患者肠道准备影响因素及相关护理干预的研究进展[J]. 护理学报,2018,25(10):41-44.DOI:10.16460/j.issn1008-9969.2018.10.041.
[52] 周英凤,胡雁,顾莺,等. 基于证据的持续质量改进模式图的构建[J]. 中国循证医学杂志, 2017, 17(5):603-606. DOI:10.7507/1672-2531.201611090.
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