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护理学报 ›› 2023, Vol. 30 ›› Issue (18): 1-5.doi: 10.16460/j.issn1008-9969.2023.18.001

• 研究生园地 •    下一篇

肺癌患者认知功能的现状及影响因素分析

骆佳慧1, 罗园园1, 方庆虹1, 叶艳欣1, 刘素婷1, 杨智慧1, 缪景霞2, 张立力1   

  1. 1.南方医科大学 护理学院,广东 广州 510515;
    2.南方医科大学南方医院 肿瘤内科,广东 广州 510515
  • 收稿日期:2022-11-01 出版日期:2023-09-25 发布日期:2023-10-11
  • 通讯作者: 张立力（1967-）,女,辽宁锦州人,博士,博士研究生导师,教授。E-mail: zhanglili_gzsmu@163.com
  • 作者简介:骆佳慧（1998-）,女,湖北孝感人,本科学历,硕士研究生在读。
  • 基金资助:
    2022年广东省大学生创新训练项目（S202212121146）; 广州市科学研究计划（201904010129）

Status quo and influencing factors of cognitive function in lung cancer patients

LUO Jia-hui1, LUO Yuan-yuan1, FANG Qing-hong1, YE Yan-xin1, LIU Su-ting1, YANG Zhi-hui1, MIAO Jing-xia2, ZHANG Li-li1   

  1. 1. School of Nursing, Southern Medical University,Guangzhou 510515, China;
    2. Dept. of Medical Oncology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
  • Received:2022-11-01 Online:2023-09-25 Published:2023-10-11

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摘要： 目的 调查肺癌患者认知功能的现状及影响因素,为识别和管理癌症相关认知障碍提供主客观依据。方法 便利选取2021年10月—2022年8月收治于某院的390例肺癌患者作为研究对象。采用一般资料调查表、癌症治疗功能评估-认知功能量表、安德森症状评估量表、营养风险评分表等进行调查。将肺癌患者认知功能得分进行基于秩次的逆正态变换后,采用多元线性回归探索其影响因素。结果 390例肺癌患者的认知功能得分为121.00（107.00,126.00）分。年龄、性别、精神情绪症状群、确诊时间、休闲活动、营养风险评分进入回归方程（P<0.05）,共解释总变异的42.4%。结论 本研究中肺癌患者自我报告的认知功能较好。精神情绪症状群、确诊时间、营养风险、休闲活动、年龄、性别是主要的影响因素。医护人员应重点评估以上因素,及时管理肺癌患者的认知功能,从而提升其生活质量。

关键词: 肺癌, 认知功能, 症状群, 营养风险, 休闲活动

Abstract: Objective To investigate the status quo and influencing factors of cognitive function in lung cancer patients, and to provide subjective and objective reference for cancer-related cognitive impairment. Methods Convenience sampling was used to select 390 lung cancer patients admitted to Nanfang Hospital from October 2021 to August 2022, and the patients were surveyed by using general information questionnaire, Functional Assessment of Cancer Therapy-Cognitive Functioning Scale (FACT-Cog), M.D. Anderson Symptom Inventory, and Nutritional Risk Rating Scale. After performing a rank-based inverse-normal transformation of the cognitive function score, multiple linear regression was used to analyze the influencing factors. Results The score of FACT-Cog of lung cancer patients was 121.00 (107.00, 126.00). Mental-emotional symptom cluster score, diagnosed time, leisure activity, NRS2002 score, sex, and age entered the regression equation, accounting for 42.4% of the total variation (P<0.05). Conclusion Self-reported cognitive function of lung cancer patients in this study maintains good. Mental-emotional symptom clusters, diagnosed time, nutritional risk, leisure activities, age, and sex are the influencing factors. Timely assessment of these factors and management of cognitive function of lung cancer patients are critical to enhancing their quality of life.

Key words: lung cancer, cognitive function, symptom cluster, nutritional risk, leisure activity

中图分类号: 

  • R473.73
[1] 张营, 孟英涛, 尚美美, 等. 癌症相关认知功能障碍评估和管理的证据总结[J]. 护理学报, 2022, 29(3):52-56. DOI:10.16460/j.issn1008-9969.2022.03.052.
[2] Ju X, Bai J, She Y, et al.Symptom cluster trajectories and sentinel symptoms during the first cycle of chemotherapy in patients with lung cancer[J]. Eur J Oncol Nurs, 2023, 63: 102282. DOI:10.1016/j.ejon.2023.102282.
[3] Eggen AC, Richard NM, Bosma I, et al.Factors associated with cognitive impairment and cognitive concerns in patients with metastatic non-small cell lung cancer[J]. Neurooncol Pract, 2022, 9(1):50-58. DOI:10.1093/nop/npab056.
[4] 胡雁, 王志稳. 护理研究[M]. 5版.北京:人民卫生出版社, 2017.
[5] Nucci M, Mapelli D, Mondini S.Cognitive Reserve Index questionnaire (CRIq): a new instrument for measuring cognitive reserve[J]. Aging Clin Exp Res, 2012, 24(3):218-226. DOI:10.3275/7800.
[6] 张彩婧. 正常老年人认知储备与认知功能的相关性研究[D].呼和浩特:内蒙古医科大学, 2019. DOI:10.27231/d.cnki.gnmyc.2019.000252.
[7] Cheung YT, Lim SR, Shwe M, et al.Psychometric properties and measurement equivalence of the English and Chinese versions of the functional assessment of cancer therapy-cognitive in Asian patients with breast cancer[J]. Value Health, 2013, 16(6):1001-1003. DOI:10.1016/j.jval.2013.06.017.
[8] Castillo-Martínez L, Castro-Eguiluz D, Copca-Mendoza ET, et al.Nutritional assessment tools for the identification of malnutrition and nutritional risk associated with cancer treatment[J]. Rev Invest Clin, 2018, 70(3):121-125. DOI:10.24875/RIC.18002524.
[9] 张立力, 臧瑜. MD安德森症状评估量表肺癌模块的修订和考评[J]. 肿瘤, 2013,33(5):434-438. DOI:10.3781/j.issn.1000-7431.2013.05.009.
[10] 叶艳欣, 秦岚, 曾凯, 等. 癌症患者治疗间歇期核心症状及症状群的识别[J]. 护理学杂志, 2022, 37(1):20-24. DO1:10.3870/j.issn.1001-4152.2022.01.020.
[11] 谢剑华, 刘苗苗, 彭丽丽, 等. 系统免疫炎症营养指数与非手术治疗老年非小细胞肺癌患者预后的关系研究[J]. 中国全科医学, 2022, 25(17):2082-2089. DOI:10.12114/j.issn.1007-9572.2022.0102.
[12] McCaw ZR, Lane JM, Saxena R, et al. Operating characteristics of the rank-based inverse normal transformation for quantitative trait analysis in genome-wide association studies[J]. Biometrics, 2020, 76(4):1262-1272. DOI:10.1111/biom.13214.
[13] Dyk KV, Crespi CM, Petersen L, et al.Identifying cancer-related cognitive impairment using the FACT-Cog Perceived Cognitive Impairment[J].JNCI Cancer Spectr, 2020, 4(1): z99. DOI:10.1093/jncics/pkz099.
[14] Li N, Lu J, Xia D, et al.Serum biomarkers predict adjuvant chemotherapy-associated symptom clusters in radical resected colorectal cancer patients[J]. J Gastrointest Oncol, 2022, 13(1): 197-209. DOI:10.21037/jgo-21-904.
[15] Whitney KA, Lysaker PH, Steiner AR, et al.Is"chemobrain" a transient state? A prospective pilot study among persons with non-small cell lung cancer[J]. J Support Oncol, 2008, 6(7):313-321.
[16] 李欢, 丁杏, 何惠敏, 等. 肺癌化疗后神经认知功能损害的影响因素分析及其与生活质量的相关性研究[J]. 临床和实验医学杂志, 2021, 20(11):1191-1195. DOI:10.3969/j.issn.1671-4695.2021.11.020.
[17] Song S, Stern Y, Gu Y.Modifiable lifestyle factors and cognitive reserve: a systematic review of current evidence[J]. Ageing Res Rev, 2022,74:101551. DOI:10.1016/j.arr.2021.101551.
[18] 任志玲, 茅乃权, 甘海洁, 等. 肺癌患者病耻感及社会支持与生活质量结构方程模型的构建[J]. 中国护理管理, 2019, 19(5):701-705.DOI:10.3969/j.issn.1672-1756.2019.05.012.
[19] Yu W, Yu W, Liu X, et al.Associations between malnutrition and cognitive impairment in an elderly Chinese population: an analysis based on a 7-year database[J]. Psychogeriatrics, 2021,21(1):80-88. DOI: 10.1111/psyg.12631.
[20] 欧阳蝶, 张男, 袁书琪, 等. 乳腺癌患者内分泌治疗期感知认知功能现况调查[J]. 护理学杂志, 2022, 37(4):28-32. DOI:10.3870/j.issn.1001—4152.2022.04.028.
[21] Tan CJ, Mah J, Goh WL, et al.Self-reported cognitive outcomes among adolescent and young adult patients with noncentral nervous system cancers[J].Psychooncology, 2020, 29(8):1355-1362. DOI:10.1002/pon.5456.
[22] Bai L, Yu E.A narrative review of risk factors and interventions for cancer-related cognitive impairment[J]. Ann Transl Med, 2021, 9(1):72. DOI:10.21037/atm-20-6443.
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