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护理学报 ›› 2024, Vol. 31 ›› Issue (24): 37-43.doi: 10.16460/j.issn1008-9969.2024.24.037

• 循证护理 • 上一篇    下一篇

不同非药物干预措施改善乳腺癌患者疲乏效果的网状Meta分析

姚婉晴1a, 杨立状2, 陈旦旦1b, 张晚秋1b, 卢薇1a, 管翠红1a, 李海2   

  1. 1.中国科学院合肥肿瘤医院 a.肿瘤智慧康复中心; b.护理部, 安徽 合肥 230088;
    2.中国科学院合肥物质科学研究院, 安徽 合肥 230031
  • 收稿日期:2024-07-08 出版日期:2024-12-25 发布日期:2025-01-09
  • 通讯作者: 杨立状（1982-）,男,山东曲阜人,博士,副研究员,硕士研究生导师。E-mail:lzyang@cmpt.ac.cn
  • 作者简介:姚婉晴（1991-）,女,安徽阜阳人,硕士,主管护师。
  • 基金资助:
    国家自然科学基金面上项目（82371931）;中国科学院合肥肿瘤医院优秀医学青年人才计划项目（YQJH2023011）;中国科学院合肥肿瘤医院管理学部软课题（GLXB202305）

Efficacy of different non-drug interventions on cancer-related fatigue in breast cancer patients: a network Meta-analysis

YAO Wan-qing1a, YANG Li-zhuang2, CHEN Dan-dan1b, ZHANG Wan-qiu1b, LU Wei1a, GUAN Cui-hong1a, LI Hai2   

  1. 1a. Smart Rehabilitation Center for Cancer; 1b. Dept. of Nursing Administration, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei 230088, China;
    2. Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China
  • Received:2024-07-08 Online:2024-12-25 Published:2025-01-09

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摘要： 目的 评价并比较不同非药物措施对乳腺癌患者疲乏的干预效果,为临床提供循证依据。方法 系统检索中国知网、万方、维普、中国生物医学文献数据库、PubMed、Medline、Web of Science、Cochrane Library数据库从建库至2024年8月关于非药物干预方式对乳腺癌患者疲乏影响的研究。使用Stata 14.0软件进行网状Meta分析。结果 最终纳入38项研究,共12种干预措施,3 901例乳腺癌患者。研究结果表明,与常规干预相比,抗阻运动联合高强度间歇运动、有氧运动联合高强度间歇运动、认知行为疗法、瑜伽、按摩对乳腺癌患者疲乏具有较好的改善效果（P<0.05）。累积排序概率图下面积显示,抗阻运动联合高强度间歇运动是改善乳腺癌患者疲乏的最佳非药物干预方式。结论 抗阻运动联合高强度间歇运动改善乳腺癌患者疲乏的效果最佳,建议临床护理优先考虑,但仍需高质量随机对照试验进行验证。

关键词: 乳腺癌, 疲乏, 非药物干预, 网状Meta分析

Abstract: Objective To evaluate and compare the efficacy of different non-drug interventions on cancer-related fatigue in breast cancer patients, and to provide evidence for the formulation of relevant intervention programs. Methods We systematically retrieved randomized controlled trials（RCT）on the effects of non-drug interventions on cancer-related fatigue in breast cancer patients from CNKI, Wanfang Data, VIP, CBM, Medline, PubMed, Web of Science, the Cochrane Library. The retrieval period spanned from the inception to August 2024. Stata14.0 was used for data analysis. Results A total of 38 studies were included,including 12 non-pharmaceutical interventions,involving 3 901 breast cancer patients. The Results showed that compared with conventional care, resistance and high-intensity interval training, aerobic and high-intensity interval exercise, cognitive behavioral therapy, yoga and massage had better effects on cancer-related fatigue in breast cancer patients(P<0.05). The area under the cumulative rank probability map showed that resistance and high-intensity interval training was the best non-drug intervention. Conclusion A combination of resistance exercise and high-intensity interval training is the most effective for alleviating fatigue in breast cancer patients, and it is recommended that clinical nursing prioritize this approach. However, a large number of high-quality RCTs are still needed for the verification.

Key words: breast neoplasm, cancer-related fatigue, non-drug intervention, network Meta-analysis

中图分类号: 

  • R473.73
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