目的 对FLS在骨质疏松性髋部骨折患者中应用的研究进行范围审查,为未来FLS的研究方向以及临床应用提供参考。方法 检索自建库至2023年11月30日中国知网、万方、维普、中国生物医学文献、中华医学期刊全文数据库、PubMed、Embase、Cochrane Library、Web of Science、CINAHL、JBI数据库中发表的所有与主题相关的文献。对作者、发表年份、国家、研究类型、样本量、干预措施、干预时长、结局指标等进行提取与汇总分析。结果 共纳入33篇文献。干预措施多以FLS团队确立、患者的识别和确认、危险因素的评估和干预、药物和非药物治疗、健康随访为框架。共提取27项结局指标,归纳为有效性结局指标、主观结局指标、安全性结局指标、医院相关结局指标4个方面。结论 骨折联络服务对骨质疏松性髋部骨折患者的预后改善及再骨折预防有积极意义。未来研究应规范干预措施、结局指标及其评价内容和工具,制定适合骨质疏松性髋部骨折患者的骨折联络服务方案。
Abstract
Objective To perform a scoping review on the application of fracture liaison service (FLS) in patients with osteoporotic hip fracture and to provide reference for FLS's clinical application and future research. Methods We searched literature in CNKI, Wanfang Data, VIP, CBM, Chinese Medical Journal Full Text Database, PubMed, Embase, Cochrane Library, Web of Science, CINAHL, and JBI databases from the inception to November 30, 2023. The following information was retrieved and extracted for the analysis: author, publication year, nation, study type, sample size, intervention, length of intervention, and outcome indicator. Results Totally 33 articles were collected. The framework of the interventions was mainly established by the establishment of FLS team, patient identification and validation, risk factor evaluation and intervention, pharmaceutical and non-pharmacological treatment, and health follow-up. A total of 27 outcome indicators were extracted and categorized into 4 aspects: effectiveness outcome indicators, subjective outcome indicators, safety outcome indicators, and hospital-related outcome indicators. Conclusion In patients with osteoporotic hip fracture, FLS has a favorable impact on prognosis improvement and re-fracture prevention. In future research, an appropriate FLS program for patients with osteoporotic hip fracture should be created, and the interventions, outcome indicators, and evaluation tools should be standardized.
关键词
骨折联络服务 /
骨质疏松症 /
髋部骨折 /
范围综述
Key words
fracture liaison service /
osteoporosis /
hip fracture /
scoping review
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参考文献
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