目的了解成人阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome,OSAHS)患者认知功能受损状况.方法采用多导睡眠监测仪检测152例OSAHS患者(观察组)睡眠呼吸情况,采用蒙特利尔认知功能评定量表评估认知功能;同时评估152例健康志愿者(对照组)认知功能,将两组得分进行比较.结果152例OSAHS患者中,认知总分<26分有113例(74.3%),对照组7例(4.6%),OSAHS患者认知功能障碍发生率显著高于对照组(字2=154.699,P=0.000);OSAHS患者认知功能总分及执行功能、命名、注意、计算、语言、抽象、延迟回忆、定向得分均低于对照组(P<0.01).结论约75%的OSAHS患者伴随不同程度的认知功能障碍,其认知功能障碍发生率显著高于健康人群;与健康人群相比,OSAHS患者总体认知功能下降,同时,执行功能、命名、注意力、语言能力、计算能力、记忆力、抽象思维能力、定向力各领域认知功能也全面受到影响,在护理过程中应引起重视.

Objective To understand cognitive function damage of patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods With polysomnography, 152 patients with OSAHS were taken as experiment group and monitored for their sleep-related breathing and