目的 总结开颅术后丙戊酸钠相关性高血氨脑病的特点及护理经验.方法 分析和总结6例开颅术后丙戊酸钠相关性高血氨脑病患者在病情变化观察、用药、安全和心理等方面的护理要点.结果 6例患者血浆氨恢复正常时间为1~3 d,5例临床症状消失,消失时间为1~3 d,4例出现迟发性肝功能损伤.结论 丙戊酸钠相关性高血氨脑病是严重的并发症.及时发现和正确判断患者是否出现丙戊酸钠相关性高血氨脑病,是护理工作难点.护士需严密观察患者的意识动态变化及精神症状的发生,配合医生及时检测丙戊酸钠血药浓度、血氨浓度,早期识别丙戊酸钠相关性高血氨脑病,做好用药、安全及心理护理.

Objective To summarize the features of valproate-induced hyperammonemic encephalopathy (VHE) and its nursing experience. Methods We analyzed and summarized the nursing points regarding to the condition observation, medication, safety and patients' psychol